CLSTN1/Calsyntenin 1 Antibody, HRP Conjugated

• Catalog number
  bs-11644R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  CLSTN1/Calsyntenin 1 Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CLSTN1/Calsyntenin 1
• Specificity
  This is a highly specific antibody against CLSTN1/Calsyntenin 1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human Calsyntenin 1
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-1, also known as CSTN1, PIK3CD, Alzheimer-related cadherin-like protein, non-classical cadherin XB31alpha, KIAA0911, ALC-ALPHA, alcalpha1, alcalpha2 or FLJ32258, is a 981 amino acid single-pass type I membrane protein that localizes to the membrane of endoplasmic reticulum, Golgi apparatus, cell projections and postsynaptic cells. Expressed in brain, calsyntenin-1 is also found at lower levels in placenta, skeletal muscle, heart and kidney. Calsyntenin-1 binds synaptic Ca2+ with its cytoplasmic domain and plays a role in extracellular proteolysis. Calsyntenin-1 is also known to form a complex with X11 Beta and APP to suppress the metabolic cleavage of APP, and docks vesicular cargo to KLC1. Calsyntenin-1 may be related to the development or progression of Alzheimer’s disease, and two calsyntenin-1 isoforms are produced as a result of alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  Alc alpha; Alc-alpha; Alcadein alpha 1; Alcadein alpha; Alcadein-alpha; alcalpha1; alcalpha2; Alzheimer related cadherin like protein; Alzheimer-related cadherin-like protein; Calsyntenin-1; Calsyntenin1; CLSTN 1; Clstn1; CS1; CSTN1; CSTN1_HUMAN; CTF1-alpha; FLJ32258; KIAA0911; Non classical cadherin XB31alpha; Non-classical cadherin XB31alpha; PIK3CD; SAlc-alpha; XB31alpha.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  CLSTN1/Calsyntenin   Conjugated  
• Gene symbol
  CLSTN1
• Short name
  Anti-CLSTN1/Calsyntenin 1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-CLSTN1/Calsyntenin 1 PAb HRP
• Alternative technique
  antibodies
• Alternative to gene target
  calsyntenin 1, ALC-ALPHA and alcalpha1 and alcalpha2 and CDHR12 and CSTN1 and PIK3CD and XB31alpha, CLSTN1 and IDBG-88646 and ENSG00000171603 and 22883, X11-like protein binding, nuclei, Clstn1 and IDBG-205238 and ENSMUSG00000039953 and 65945, CLSTN1 and IDBG-633317 and ENSBTAG00000011823 and 514447

Gene info

• Identity
  HGNC:17447
• Gene
  CLSTN1
• Long gene name
  calsyntenin 1
• Synonyms
  • CSTN1
  • KIAA0911
  • CDHR12
• Synonyms name
  • cadherin-related family member 12
• GenBank acession
  • AB020718
• Locus
  1p36.22
• Discovery year
  2002-05-01
• Entrez gene record
  22883
• Pubmed identfication
  • 10048485
• Classification
  • Cadherin related
• VEGA ID
  OTTHUMG00000001451

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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