CLSTN1/Calsyntenin 1 Antibody, Cy7 Conjugated

• Catalog number
  bs-11644R-Cy7
• Price
  Please ask
• Size
  0.1ml

• Long name
  CLSTN1/Calsyntenin 1 Polyclonal Antibody, Cy7 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy7
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CLSTN1/Calsyntenin 1
• Specificity
  This is a highly specific antibody against CLSTN1/Calsyntenin 1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human Calsyntenin 1
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-1, also known as CSTN1, PIK3CD, Alzheimer-related cadherin-like protein, non-classical cadherin XB31alpha, KIAA0911, ALC-ALPHA, alcalpha1, alcalpha2 or FLJ32258, is a 981 amino acid single-pass type I membrane protein that localizes to the membrane of endoplasmic reticulum, Golgi apparatus, cell projections and postsynaptic cells. Expressed in brain, calsyntenin-1 is also found at lower levels in placenta, skeletal muscle, heart and kidney. Calsyntenin-1 binds synaptic Ca2+ with its cytoplasmic domain and plays a role in extracellular proteolysis. Calsyntenin-1 is also known to form a complex with X11 Beta and APP to suppress the metabolic cleavage of APP, and docks vesicular cargo to KLC1. Calsyntenin-1 may be related to the development or progression of Alzheimer’s disease, and two calsyntenin-1 isoforms are produced as a result of alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  743nm/767nm
• Synonyms
  Alc alpha; Alc-alpha; Alcadein alpha 1; Alcadein alpha; Alcadein-alpha; alcalpha1; alcalpha2; Alzheimer related cadherin like protein; Alzheimer-related cadherin-like protein; Calsyntenin-1; Calsyntenin1; CLSTN 1; Clstn1; CS1; CSTN1; CSTN1_HUMAN; CTF1-alpha; FLJ32258; KIAA0911; Non classical cadherin XB31alpha; Non-classical cadherin XB31alpha; PIK3CD; SAlc-alpha; XB31alpha.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugated
  These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
• Additional conjugation
  Cy7
• French translation
  anticorps

• Gene target
  CLSTN1/Calsyntenin   Conjugated  
• Gene symbol
  CLSTN1
• Short name
  Anti-CLSTN1/Calsyntenin 1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy7
• Alternative name
  Anti-CLSTN1/Calsyntenin 1 PAb Cy7
• Alternative technique
  antibodies
• Alternative to gene target
  calsyntenin 1, ALC-ALPHA and alcalpha1 and alcalpha2 and CDHR12 and CSTN1 and PIK3CD and XB31alpha, CLSTN1 and IDBG-88646 and ENSG00000171603 and 22883, X11-like protein binding, nuclei, Clstn1 and IDBG-205238 and ENSMUSG00000039953 and 65945, CLSTN1 and IDBG-633317 and ENSBTAG00000011823 and 514447

Gene info

• Identity
  HGNC:17447
• Gene
  CLSTN1
• Long gene name
  calsyntenin 1
• Synonyms
  • CSTN1
  • KIAA0911
  • CDHR12
• Synonyms name
  • cadherin-related family member 12
• GenBank acession
  • AB020718
• Locus
  1p36.22
• Discovery year
  2002-05-01
• Entrez gene record
  22883
• Pubmed identfication
  • 10048485
• Classification
  • Cadherin related
• VEGA ID
  OTTHUMG00000001451

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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