CEA (5F2) Antibody, Biotin Conjugated
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Catalog numberbsm-4793M-Biotin
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PricePlease ask
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Size0.1ml
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Long nameCEA (5F2) Monoclonal Antibody, Biotin Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationBiotin
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Host OrganismMouse (Mus musculus)
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Target AntigenCEA
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SpecificityThis is a highly specific antibody against CEA.
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ModificationUnmodified
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Modification siteNone
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ClonalityMonoclonal
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Clone5F2
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic peptide derived from Human CEA/CEACAM5
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Gene ID number1048
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Tested applicationsWB, IHC-P
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500)
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CrossreactivityHuman
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundCEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
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Purification methodPurified by Protein G.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation EmissionN/A
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SynonymsCarcino Embryonic Antigen CEA; CEACAM 5; CEACAM-5; Carcinoembryonic antigen; Carcinoembryonic antigen related cell adhesion molecule 5; CD66e; CD66e antigen; CEA; CEACAM5; DKFZp781M2392; Meconium antigen 100.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
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Additional conjugationBiotinylated
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French translationanticorps
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Gene target
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Gene symbolCEACAM7, CEACAM5, PSG2
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Short nameAnti-CEA
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelBiotin
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Alternative nameAnti-CEA MAb Biotin
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameCEA cell adhesion molecule 7
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Synonyms gene
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Synonyms gene name
- carcinoembryonic antigen-related cell adhesion molecule 7
- carcinoembryonic antigen related cell adhesion molecule 7
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-09-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- V-set domain containing
- CEA cell adhesion molecule family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCEA cell adhesion molecule 5
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Synonyms gene
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Synonyms gene name
- carcinoembryonic antigen-related cell adhesion molecule 5
- carcinoembryonic antigen related cell adhesion molecule 5
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Synonyms
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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RefSeq identity
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Classification
- I-set domain containing
- V-set domain containing
- CEA cell adhesion molecule family
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepregnancy specific beta-1-glycoprotein 2
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Synonyms gene
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Synonyms
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Synonyms name
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Locus
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Discovery year1991-06-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pregnancy specific glycoproteins
- V-set domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data