Caspase 4+Caspase 11 Antibody, Biotin Conjugated

  • Catalog number
    bs-6858R-Biotin
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    Caspase 4+Caspase 11 Polyclonal Antibody, Biotin Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Biotin
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Caspase 4+Caspase 11
  • Specificity
    This is a highly specific antibody against Caspase 4+Caspase 11.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic peptide derived from mouse Caspase-4 subunit p20
  • Gene ID number
    837
  • Tested applications
    WB, IHC-P
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500)
  • Crossreactivity
    Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Caspase 11 (also known as ICH3) gene encodes two protein products of 38 and 43 kDa that belong to the Ced3/ICE family of cysteine proteases. Caspase 11 is an “upstream†caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits. Monoclonal reacting specifically with caspase 11 are useful tools for the study of the protease network, involved in development and regulation, governing the life and death of cells and tissues.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    N/A
  • Synonyms
    CASP11;CASP11;Casp4;Caspase 11;Caspase11;Caspase-11;Caspase 4;Caspase4;Caspase-4;Caspase 4 apoptosis related cysteine peptidase;CASPL;CASPL;Ich3;ICH3 protease;ICH3 protease.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
  • Additional conjugation
    Biotinylated
  • Description
    Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
  • French translation
    anticorps
  • Gene target
  • Short name
    Anti-Caspase 4+Caspase 11
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    Biotin
  • Alternative name
    Anti-Caspase 4+Caspase 11 PAb Biotin
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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