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Long name
Calcineurin B (Tyr106) Antibody, Cy5.5 Conjugated
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Category
Conjugated Primary Antibodies
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Conjugation
Cy5.5
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
Calcineurin B Tyr106
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Specificity
This is a highly specific antibody against Calcineurin B Tyr106.
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Modification
Phosphorylation
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Modification site
Tyr106
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated syntheticphosphopeptide derived from human Calcineurin B around the phosphorylation site of Tyr106
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Gene ID number
5534
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen background
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-A alpha, PP2B-A Beta and PP2B-A Gamma. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission
675nm/694nm
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Synonyms
Calcineurin B phospho Y106; Calcineurin B phospho Tyr106; p-Calcineurin B Tyr106; Calcineurin subunit B type 1; CALNB1; CANB1_HUMAN; Cna2; CNB; CNB1; OTTHUMP00000201960; OTTHUMP00000201961; Ppp3r1; PPP3R1 protein phosphatase 3 formerly 2B, regulatory subunit B, alpha isoform; alpha isoform calcineurin B, type I; calcineurin B, type I 19kDa; protein phosphatase3 formerly2B, regulatory subunit B, alpha isoform antibody Protein phosphatase 2B regulatory subunit 1; Protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 formerly 2B, regulatory subunit B, 19kDa, alpha isoform calcineurin B, type I; Protein phosphatase 3 regulatory subunit B alpha; Protein phosphatase 3 regulatory subunit B alpha isoform 1.
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Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
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Additional conjugation
Cy5.5, Cy5.5
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Conjugated
These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
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French translation
anticorps