BMP10 Antibody, Biotin Conjugated

• Catalog number
  bs-9447R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  BMP10 Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  BMP10
• Specificity
  This is a highly specific antibody against BMP10.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  350-400/424
• Subcellular location
  Secreted
• Source
  KLH conjugated synthetic peptide derived from human BMP10
• Gene ID number
  27302
• Swiss Prot
  O95393
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  Bone morphogenetic protein 1; BMP-1; BMP1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  BMP10   Conjugated  
• Gene symbol
  BMP10
• Short name
  Anti-BMP10
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-BMP10 PAb Biotin
• Alternative technique
  antibodies
• Alternative to gene target
  bone morphogenetic protein 10, BMP10 and IDBG-54663 and ENSG00000163217 and 27302, receptor serine/threonine kinase binding, Extracellular, Bmp10 and IDBG-165762 and ENSMUSG00000030046 and 12154, BT.106443 and IDBG-635729 and ENSBTAG00000000992 and 538874

Gene info

• Identity
  HGNC:20869
• Gene
  BMP10
• Long gene name
  bone morphogenetic protein 10
• GenBank acession
  • AF101441
• Locus
  2p13.3
• Discovery year
  2003-04-16
• Entrez gene record
  27302
• Pubmed identfication
  • 10072785
• RefSeq identity
  • NM_014482
• Classification
  • Bone morphogenetic proteins
• VEGA ID
  OTTHUMG00000129573
• Locus Specific Databases
  • LRG_403

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products