beta Amyloid 1-42 Antibody, FITC Conjugated

• Catalog number
  bs-0107R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  beta Amyloid 1-42 Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  beta Amyloid 1-42
• Specificity
  This is a highly specific antibody against beta Amyloid 1-42.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  672-713/770
• Subcellular location
  Extracellular, Secreted
• Source
  KLH conjugated synthetic peptide of human beta-Amyloid(1-42)
• Gene ID number
  351
• Swiss Prot
  P05067
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; Amyloid beta A4 protein; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; PreA4; Protease nexin-II; A4
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  beta   Amyloid   1-42   Conjugated  
• Gene symbol
  SNORD115-42, IGLVI-42, IGKV1D-42, IGHV3-42, RNU6-42P, DSCAM, NFX1, KIR2DL1, IGHVII-1-1, MIR1-1
• Short name
  Anti-beta Amyloid 1-42
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-beta Amyloid 1-42 PAb FITC
• Alternative technique
  antibodies, fluorescine

Gene info

• Identity
  HGNC:33061
• Gene
  SNORD115-42
• Long gene name
  small nucleolar RNA, C/D box 115-42
• Synonyms
  • HBII-52-42
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033816
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003357.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5936
• Gene
  IGLVI-42
• Long gene name
  immunoglobulin lambda variable (I)-42 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable (I)-42
  • immunoglobulin lambda variable (I)-42 pseudogene
• Synonyms
  • IGLV(I)-42
• GenBank acession
  • X14613
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28767
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151043

Gene info

• Identity
  HGNC:5757
• Gene
  IGKV1D-42
• Long gene name
  immunoglobulin kappa variable 1D-42 (non-functional)
• Synonyms gene name
  • immunoglobulin kappa variable 1D-42
• GenBank acession
  • X72816
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28892
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151573

Gene info

• Identity
  HGNC:5603
• Gene
  IGHV3-42
• Long gene name
  immunoglobulin heavy variable 3-42 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable 3-42
  • immunoglobulin heavy variable 3-42 pseudogene
• GenBank acession
  • M99671
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28427
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152081

Gene info

• Identity
  HGNC:34286
• Gene
  RNU6-42P
• Long gene name
  RNA, U6 small nuclear 42, pseudogene
• Synonyms gene
  • RNU6-42
• Synonyms gene name
  • RNA, U6 small nuclear 42
• Locus
  3q29
• Discovery year
  2008-06-10
• Entrez gene record
  100302742
• RefSeq identity
  • NR_028373

Gene info

• Identity
  HGNC:3039
• Gene
  DSCAM
• Long gene name
  DS cell adhesion molecule
• Synonyms gene name
  • Down syndrome cell adhesion molecule
• Synonyms
  • CHD2-42
  • CHD2-52
• GenBank acession
  • AF023449
• Locus
  21q22.2
• Discovery year
  1998-06-10
• Entrez gene record
  1826
• Pubmed identfication
  • 9426258
• RefSeq identity
  • NM_001389
• Classification
  • Ig-like cell adhesion molecule family
  • I-set domain containing
  • Fibronectin type III domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000086732

Gene info

• Identity
  HGNC:7803
• Gene
  NFX1
• Long gene name
  nuclear transcription factor, X-box binding 1
• Synonyms
  • NFX2
  • MGC20369
  • Tex42
  • TEG-42
• GenBank acession
  • U19759
• Locus
  9p12
• Discovery year
  1998-05-26
• Pubmed identfication
  • 7964459
  • 2511169
  • 12047746
• Classification
  • PHD finger proteins
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000019772

Gene info

• Identity
  HGNC:6329
• Gene
  KIR2DL1
• Long gene name
  killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
• Synonyms gene name
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
• Synonyms
  • cl-42
  • nkat1
  • 47.11
  • p58.1
  • CD158A
• GenBank acession
  • L41267
• Locus
  19q13.42
• Discovery year
  1997-11-14
• Entrez gene record
  3802
• Pubmed identfication
  • 7749980
  • 7716543
• RefSeq identity
  • NM_014218
• Classification
  • Killer cell immunoglobulin like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000065885
• Locus Specific Databases
  • IPD-KIR Database

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

MeSH Data

• Name
  Cytophotometry
• Concept
  Scope note: A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
• Tree numbers
  • E01.370.225.500.386
  • E05.196.712.516.600.240
  • E05.200.500.386
  • E05.242.386
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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