BCL-2 (1A5) Antibody, HRP Conjugated

• Catalog number
  bsm-10846M-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  BCL-2 (1A5) Monoclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  BCL-2
• Specificity
  This is a highly specific antibody against BCL-2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Monoclonal
• Clone
  1A5
• Concentration
  1ug per 1ul
• Source
  Recombinant protein fragment (1-220 amino acids range) of human Bcl-2.
• Gene ID number
  596
• Swiss Prot
  P10415
• Tested applications
  WB
• Recommended dilutions
  WB(1:100-1000)
• Crossreactivity
  Human, Mouse
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release
• Purification method
  Purified by Protein G.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  Apoptosis regulator Bcl-2; BCL2
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  BCL-2   1A5   Conjugated  
• Gene symbol
  BCL2, BCL2L1, BCL2L13, BCL2L10, BCL2L14, BCL2L2, MIR1289-2, MIR521-2, MIR509-2, MIR512-2
• Short name
  Anti-BCL-2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-BCL-2 MAb HRP
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:990
• Gene
  BCL2
• Long gene name
  BCL2 apoptosis regulator
• Synonyms gene name
  • B-cell CLL/lymphoma 2
  • BCL2, apoptosis regulator
• Synonyms
  • Bcl-2
  • PPP1R50
• Synonyms name
  • protein phosphatase 1, regulatory subunit 50
• GenBank acession
  • M14745
• Locus
  18q21.33
• Discovery year
  2001-06-22
• Entrez gene record
  596
• RefSeq identity
  • NM_000633
  • NM_000657
• Classification
  • BCL2 family
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000132791
• Locus Specific Databases
  • LRG_1113

Gene info

• Identity
  HGNC:992
• Gene
  BCL2L1
• Long gene name
  BCL2 like 1
• Synonyms
  • BCLX
  • BCL2L
  • Bcl-X
  • bcl-xL
  • bcl-xS
  • PPP1R52
• Synonyms name
  • protein phosphatase 1, regulatory subunit 52
• GenBank acession
  • Z23115
• Locus
  20q11.21
• Discovery year
  1997-10-30
• Entrez gene record
  598
• Pubmed identfication
  • 8358789
• RefSeq identity
  • NM_138578
• Classification
  • BCL2 family
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000032192

Gene info

• Identity
  HGNC:17164
• Gene
  BCL2L13
• Long gene name
  BCL2 like 13
• Synonyms gene name
  • BCL2-like 13 (apoptosis facilitator)
• Synonyms
  • MIL1
  • BCL-RAMBO
• GenBank acession
  • AF146568
• Locus
  22q11.21
• Discovery year
  2002-09-20
• Entrez gene record
  23786
• Pubmed identfication
  • 11262395
  • 11381032
  • 26146385
• RefSeq identity
  • NM_015367
• Classification
  • BCL2 family
• VEGA ID
  OTTHUMG00000150088

Gene info

• Identity
  HGNC:993
• Gene
  BCL2L10
• Long gene name
  BCL2 like 10
• Synonyms gene name
  • BCL2-like 10 (apoptosis facilitator)
• Synonyms
  • Diva
  • Boo
  • BCL-B
• GenBank acession
  • AF285092
• Locus
  15q21.2
• Discovery year
  1999-05-21
• Entrez gene record
  10017
• Pubmed identfication
  • 9829980
  • 9878060
• Classification
  • BCL2 family
• VEGA ID
  OTTHUMG00000131893

Gene info

• Identity
  HGNC:16657
• Gene
  BCL2L14
• Long gene name
  BCL2 like 14
• Synonyms gene name
  • BCL2-like 14 (apoptosis facilitator)
• Synonyms
  • BCLG
  • BCL-G
• GenBank acession
  • AF281254
• Locus
  12p13.2
• Discovery year
  2004-02-09
• Entrez gene record
  79370
• Pubmed identfication
  • 11054413
• RefSeq identity
  • NM_030766
• Classification
  • BCL2 family
• VEGA ID
  OTTHUMG00000159528

Gene info

• Identity
  HGNC:995
• Gene
  BCL2L2
• Long gene name
  BCL2 like 2
• Synonyms
  • KIAA0271
  • BCL-W
  • PPP1R51
• Synonyms name
  • protein phosphatase 1, regulatory subunit 51
• GenBank acession
  • D87461
• Locus
  14q11.2
• Discovery year
  1997-07-22
• Entrez gene record
  599
• Pubmed identfication
  • 8761287
• RefSeq identity
  • NM_004050
• Classification
  • BCL2 family
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000028738

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products