ACVRL1 Antibody, FITC Conjugated

• Catalog number
  bs-6020R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  ACVRL1 Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  ACVRL1
• Specificity
  This is a highly specific antibody against ACVRL1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  30-80/503
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human ALK1
• Gene ID number
  94
• Swiss Prot
  P37023
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1; Serine/threonine-protein kinase receptor R3; Activin receptor-like kinase 1; TGF-B superfamily receptor type I; ACVRL1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  ACVRL1   Conjugated  
• Gene symbol
  ACVRL1
• Short name
  Anti-ACVRL1
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-ACVRL1 PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  activin A receptor type II-like 1, ACVRLK1 and ALK-1 and ALK1 and HHT and HHT2 and ORW2 and SKR3 and TSR-I, ACVRL1 and IDBG-33826 and ENSG00000139567 and 102723650,94, transforming growth factor beta receptor activity, Cell surfaces, Acvrl1 and IDBG-185502 and ENSMUSG00000000530 and 11482, BT.28710 and IDBG-632173 and ENSBTAG00000013843 and 534536

Gene info

• Identity
  HGNC:175
• Gene
  ACVRL1
• Long gene name
  activin A receptor like type 1
• Synonyms gene
  • ACVRLK1
  • ORW2
• Synonyms gene name
  • activin A receptor type II-like 1
  • activin A receptor type IL
• Synonyms
  • HHT2
  • ALK1
  • HHT
• Synonyms name
  • activin receptor-like kinase 1
• GenBank acession
  • L17075
• Locus
  12q13.13
• Discovery year
  1994-12-12
• Entrez gene record
  94
• Pubmed identfication
  • 8397373
  • 8640225
  • 22718755
• RefSeq identity
  • NM_000020
• Classification
  • Type 1 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000169507
• Locus Specific Databases
  • Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database
  • LRG_543

MeSH Data

• Name
  Cytophotometry
• Concept
  Scope note: A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
• Tree numbers
  • E01.370.225.500.386
  • E05.196.712.516.600.240
  • E05.200.500.386
  • E05.242.386
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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