Acetyl and Histone H3(Ac-K10/p-Ser11) Antibody, Cy5.5 Conjugated
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Catalog number
bs-3748R-Cy5.5
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Price
Please ask
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Size
0.1ml
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Long name
Acetyl and Histone H3(Ac-K10/p-Ser11) Antibody, Cy5.5 Conjugated
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Category
Conjugated Primary Antibodies
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Conjugation
Cy5.5
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
Acetyl and Histone H3(Ac-K10/p-Ser11)
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Specificity
This is a highly specific antibody against Acetyl and Histone H3(Ac-K10/p-Ser11).
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Modification
Acetylation
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Modification site
Ac-K10/p-Ser11
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic peptide derived from human Acetyl and Histone H3 (Ac-Lys10/p-Ser11)
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen background
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission
675nm/694nm
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Synonyms
H3 histone family member E pseudogene; H3F3; HIST3H3; Histone H3 3 pseudogene.
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Description
N terminal acetylation or CH3CO as epigenetic regulation of Anti-Acetyl and Histone H3(Ac-K10/p-Ser11) by NATs.
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Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
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Additional conjugation
Cy5.5, Cy5.5
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Conjugated
These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
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French translation
anticorps
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Gene target
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Gene symbol
KRT10
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Short name
Anti-Acetyl and Histone H3(Ac-K10/p-Ser11)
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Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
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Isotype
Immunoglobulin G (IgG)
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Label
Cy5.5
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Alternative name
Anti-Acetyl and Histone H3(Ac-K10/p-Ser11) PAb Cy5.5
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
keratin 10
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Synonyms gene
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Synonyms gene name
- keratosis palmaris et plantaris
- keratin 10, type I
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1988-08-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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