-
Long name
VLDL Receptor Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
-
Also known as
Anti-VLDL Receptor PAb ALEXA FLUOR 350
-
Category
Conjugated Primary Antibodies
-
Conjugated with
ALEXA FLUOR® 350
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
VLDL Receptor
-
Specificity
This is a highly specific antibody against VLDL Receptor.
-
Modification
Unmodified
-
Modification Site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Immunogen range
555-605/873
-
Subcellular location
Extracellular
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human VLDL Receptor
-
Gene ID Number
7436
-
Swiss Prot
P98155
-
Tested applications
FCM, IF(IHC-P)
-
Recommended dilutions
FCM(1:20-100), IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigen
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
-
Purification
Purified by Protein A.
-
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission
343nm/442nm
-
Synonyms
CARMQ1; CHRMQ1; VLDLRCH; Very low-density lipoprotein receptor; VLDL receptor; VLDL-R; VLDLR
-
Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugation
Alexa Fluor, ALEXA FLUOR 350
-
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
French translation
anticorps