Trypsin Inhibitor Antibody, ALEXA FLUOR 555

• Catalog number
  bs-11177R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  Trypsin Inhibitor Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-Trypsin Inhibitor PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Trypsin Inhibitor
• Specificity
  This is a highly specific antibody against Trypsin Inhibitor.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Trypsin Inhibitor
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-8 (Cysteine-rich secretory protein 8), also known as PI15 (Peptidase inhibitor 15), P25TI or SugarCrisp, is a 258 amino acid secreted protein that belongs to the CRISP family. Expressed at low levels in thyroid, prostate, salivary and mammary tissue, CRISP-8 functions as a serine protease inhibitor that exhibits weak inhibitory action against Trypsin, a serine protease found in the digestive system. In addition to its role as a protease inhibitor, CRISP-8 is secreted in neuroblastoma and glioblastoma cell lines, suggesting a role for CRISP-8 in tumor formation and metastasis within the central nervous system.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  Peptidase inhibitor 15; PI-15; 25 kDa trypsin inhibitor; p25TI; Cysteine-rich secretory protein 8; CRISP-8; SugarCrisp; PI15_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
• French translation
  anticorps

• Gene target
  Trypsin   Inhibitor  
• Gene symbol
  SPINK2, ITIH5, ITIH6
• Short name
  Anti-Trypsin Inhibitor
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  Trypsin Inhibitor Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11245
• Gene
  SPINK2
• Long gene name
  serine peptidase inhibitor Kazal type 2
• Synonyms gene name
  • serine protease inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
• Synonyms
  • HUSI-II
• Synonyms name
  • acrosin-trypsin inhibitor
• GenBank acession
  • BC022514
• Locus
  4q12
• Discovery year
  1993-12-01
• Entrez gene record
  6691
• Pubmed identfication
  • 8428671
• RefSeq identity
  • NM_021114
• Classification
  • Serine peptidase inhibitors, Kazal type
• VEGA ID
  OTTHUMG00000128769

Gene info

• Identity
  HGNC:21449
• Gene
  ITIH5
• Long gene name
  inter-alpha-trypsin inhibitor heavy chain 5
• Synonyms gene name
  • inter-alpha (globulin) inhibitor H5
  • inter-alpha-trypsin inhibitor heavy chain family, member 5
• Synonyms
  • MGC10848
• Locus
  10p14
• Discovery year
  2004-01-28
• Entrez gene record
  80760
• Pubmed identfication
  • 14744536
• RefSeq identity
  • NM_030569
• Classification
  • Inter-alpha-trypsin inhibitor heavy chains
• VEGA ID
  OTTHUMG00000017635

Gene info

• Identity
  HGNC:28907
• Gene
  ITIH6
• Long gene name
  inter-alpha-trypsin inhibitor heavy chain family member 6
• Synonyms gene
  • ITIH5L
• Synonyms gene name
  • inter-alpha (globulin) inhibitor H5-like
  • inter-alpha-trypsin inhibitor heavy chain family, member 6
• Synonyms
  • UNQ6369
• GenBank acession
  • AY358170
• Locus
  Xp11.22
• Discovery year
  2004-08-16
• Entrez gene record
  347365
• Pubmed identfication
  • 12975309
• RefSeq identity
  • NM_198510
• Classification
  • Inter-alpha-trypsin inhibitor heavy chains
• VEGA ID
  OTTHUMG00000021634
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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