TRPV3 Antibody, ALEXA FLUOR 555
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Catalog numberbs-12097R-A555
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PricePlease ask
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Size100ul
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Long nameTRPV3 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
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Also known asAnti-TRPV3 PAb ALEXA FLUOR 555
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 555
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenTRPV3
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SpecificityThis is a highly specific antibody against TRPV3.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPV3
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Tested applicationsFCM, IF(IHC-P)
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Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenTransient receptor potential (TRP) proteins are cation-sensitive channels that modulate a myriad of cellular functions, including temperature sensation and vasoregulation Transcribed from a gene adjacent to VR-1, the thermal-sensitive, capsaicin-insensitive TRPV3 is expressed at warm temperatures; expression increases in response to noxious temperatures. Human TRPV3 is expressed in skin, tongue, dorsal root ganglion, trigeminal ganglion, spinal cord and brain. In addition, TRPV3 is co-expressed in dosal root ganglion neurons with VR-1. TRPV3 associates with VR-1 and may modulate VR-1 activity. The 729 amino acid TRPV5 (ECAC1) protein comprises six transmembrane domains, multiple potential phosphorylation sites, an N-linked glycosylation site and three ankyrin repeat regions. It is abundantly expressed in kidney, jejunum and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum. TRPV5 controls the rate-limiting step of vitamin D3-regulated Ca2+ reabsorption in kidney and intestine; the 5’-flanking region of TRPV5 contains four putative vitamin D3-responsive elements.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission553nm/568nm
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Synonyms1110036I10Rik; MGC124324; MGC124325; Transient receptor potential cation channel subfamily V member 3; TrpV3; Trpv3 heat sensitive channel; TRPV3_HUMAN; Vanilloid receptor 3; Vanilloid receptor like 3; Vanilloid receptor-like 3; vanilloid receptor-related osmotically activated channel protein; VRL 3; VRL-3; VRL3.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 555
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French translationanticorps
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Gene target
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Gene symbolTRPV3
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Short nameAnti-TRPV3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 555
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Alternative nameTRPV3 Polyclonal Antibody, ALEXA FLUOR 555
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nametransient receptor potential cation channel subfamily V member 3
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Synonyms gene name
- transient receptor potential cation channel, subfamily V, member 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-07-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ankyrin repeat domain containing
- Transient receptor potential cation channels
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data