Torsin A Antibody, ALEXA FLUOR 647

• Catalog number
  bs-11490R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  Torsin A Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-Torsin A PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Torsin A
• Specificity
  This is a highly specific antibody against Torsin A.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Torsin A
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  A mutation of the DYT1 gene, which codes for TorsinA, has been identified as the cause of one form of autosomal dominantly inherited dystonia. Early-onset torsion dystonia is a movement disorder, characterized by twisting muscle contractures, that begins in childhood. Symptoms are believed to result from altered neuronal communication in the basal ganglia. TorsinA comprises 332 amino acids. TorsinA is widely expressed throughout the mouse central nervous system and is detected in the majority of neurons in nearly all regions. The proteins display cytoplasmic distribution, although in some types of neurons localization is perinuclear. TorsinA often performs chaperone-like functions that assist in the assembly, operation, or dis-assembly of protein complexes. The gene which encodes TorsinA has high homology to three additional mammalian genes and a nematode gene and distal similarity to the family of heat-shock proteins and the Clp protease family. The gene which encodes TorsinA maps to human chromosome 9q34.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  DQ2; Dystonia 1; Dystonia 1 protein; Dyt1; Tor1a; Torsin A; Torsin family 1 member A; TOR1A_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-Torsin A exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  Torsin  
• Gene symbol
  TOR1A, TOR2A, TOR3A
• Short name
  Anti-Torsin A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  Torsin A Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3098
• Gene
  TOR1A
• Long gene name
  torsin family 1 member A
• Synonyms gene
  • DYT1
• Synonyms gene name
  • dystonia 1, torsion (autosomal dominant; torsin A)
  • torsin family 1, member A (torsin A)
• Synonyms
  • DQ2
• Synonyms name
  • torsin A
• GenBank acession
  • AF007871
• Locus
  9q34.11
• Discovery year
  1987-09-11
• Entrez gene record
  1861
• Pubmed identfication
  • 10644435
• RefSeq identity
  • NM_000113
• Classification
  • Torsins
• VEGA ID
  OTTHUMG00000020794
• Locus Specific Databases
  • LRG_1029

Gene info

• Identity
  HGNC:11996
• Gene
  TOR2A
• Long gene name
  torsin family 2 member A
• Synonyms gene name
  • torsin family 2, member A
• Synonyms
  • FLJ14771
  • TORP1
• GenBank acession
  • AA873275
• Locus
  9q34.11
• Discovery year
  2000-02-17
• Entrez gene record
  27433
• Pubmed identfication
  • 10644435
• RefSeq identity
  • NM_130459
• Classification
  • Torsins
• VEGA ID
  OTTHUMG00000020706

Gene info

• Identity
  HGNC:11997
• Gene
  TOR3A
• Long gene name
  torsin family 3 member A
• Synonyms gene
  • ADIR
• Synonyms gene name
  • ATP-dependant interferon responsive
  • torsin family 3, member A
• Synonyms
  • FLJ22345
  • ADIR2
• GenBank acession
  • BC001085
• Locus
  1q25.2
• Discovery year
  2000-02-17
• Entrez gene record
  64222
• Pubmed identfication
  • 10644435
• RefSeq identity
  • NM_022371
• Classification
  • Torsins
  • Minor histocompatibility antigens
• VEGA ID
  OTTHUMG00000035077

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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