TORC2 (Ser171) Antibody, ALEXA FLUOR 350

• Catalog number
  bs-3415R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  TORC2 (Ser171) Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-TORC2 Ser171 PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  TORC2 Ser171
• Specificity
  This is a highly specific antibody against TORC2 Ser171.
• Modification
  Phosphorylation
• Modification Site
  Ser171
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  150-190/693
• Subcellular location
  Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171
• Gene ID Number
  200186
• Swiss Prot
  Q53ET0
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  TORC2; TORC-2; CREB-regulated transcription coactivator 2; Transducer of regulated cAMP response element-binding protein 2; Transducer of CREB protein 2; CRTC2
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• French translation
  anticorps

• Gene target
  TORC2   Ser171  
• Gene symbol
  CRTC2
• Short name
  Anti-TORC2 Ser171
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  TORC2 (Ser171) Polyclonal Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:27301
• Gene
  CRTC2
• Long gene name
  CREB regulated transcription coactivator 2
• Synonyms
  • TORC2
• GenBank acession
  • AY360172
• Locus
  1q21.3
• Discovery year
  2005-11-24
• Entrez gene record
  200186
• Pubmed identfication
  • 14506290
  • 14536081
• RefSeq identity
  • NM_181715
• VEGA ID
  OTTHUMG00000037156

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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