TIE2 (Tyr1102) Antibody, ALEXA FLUOR 555
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Catalog numberbs-12263R-A555
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Price:
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Size100ul
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Long nameTIE2 (Tyr1102) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
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Also known asAnti-TIE2 Tyr1102 PAb ALEXA FLUOR 555
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 555
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenTIE2 Tyr1102
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SpecificityThis is a highly specific antibody against TIE2 Tyr1102.
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ModificationPhosphorylation
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Modification SiteTyr1102
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from human TIE2 around the phosphorylation site of Tyr1102
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Gene ID Number7010
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenThe TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.TEK is closely related to the TIE receptor tyrosine kinase.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission553nm/568nm
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Synonymsp-TIE2 phospho Y1102; Angiopoietin-1 receptor; CD202b; CD202b antigen; Endothelial tyrosine kinase; Endothelium specic receptor tyrosine kinase 2; hTIE 2; hTIE2; hTIE2; Hyk; p140 TEK; p140 TEK; Tek; tek tyrosine kinase; TEK tyrosine kinase endothelial; tek tyrosine kinase, endothelial; TIE 2; TIE2_HUMAN; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains 2; Tyrosine protein kinase receptor TEK; Tyrosine protein kinase receptor TIE 2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; Venous malformations multiple cutaneous and mucosal; VMCM 1; VMCM; VMCM1.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 555
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French translationanticorps
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Gene target
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Gene symbolTEK
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Short nameAnti-TIE2 Tyr1102
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 555
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Alternative nameTIE2 (Tyr1102) Polyclonal Antibody, ALEXA FLUOR 555
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameTEK receptor tyrosine kinase
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Synonyms gene
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Synonyms gene name
- venous malformations, multiple cutaneous and mucosal
- TEK tyrosine kinase, endothelial
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1994-05-24
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Entrez gene record
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Pubmed identfication
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Classification
- Receptor tyrosine kinases
- Fibronectin type III domain containing
- CD molecules
- Immunoglobulin like domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data