Talin Antibody, ALEXA FLUOR 594

• Catalog number
  bs-3619R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  Talin Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-Talin1 + 2 PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Talin1 + 2
• Specificity
  This is a highly specific antibody against Talin1 + 2.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  1610-1660/2541
• Subcellular location
  Cytoplasm, Cell membrane
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Talin 1.
• Gene ID Number
  7094, 83660
• Swiss Prot
  Q9Y4G6, Q9Y490
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-270 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin. Talin and vinculin have been shown to interact with each other and both have been proposed to be involved in generating the transmembrane connection, between the extracellular matrix and the cytoskeleton, that occurs at adhesion plaques. At physiological ionic strength, talin is an elongate, flexible, monomeric protein with the ability to self-associate into dimers at higher protein concentrations.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  TLN 1; ILWEQ; Talin 1; Talin; TLN; TLN1; TLN 2; Talin 2; Talin 2; TLN2.
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  Talin  
• Gene symbol
  TLN2, TLN1, TLNRD1
• Short name
  Anti-Talin1 + 2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  Talin Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:15447
• Gene
  TLN2
• Long gene name
  talin 2
• Synonyms
  • KIAA0320
  • ILWEQ
• GenBank acession
  • AB002318
• Locus
  15q22.2
• Discovery year
  2001-04-25
• Entrez gene record
  83660
• Pubmed identfication
  • 9205841
  • 11527381
• Classification
  • FERM domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133679

Gene info

• Identity
  HGNC:11845
• Gene
  TLN1
• Long gene name
  talin 1
• Synonyms gene
  • TLN
• Synonyms
  • ILWEQ
• GenBank acession
  • AB028950
• Locus
  9p13.3
• Discovery year
  1996-10-31
• Entrez gene record
  7094
• Pubmed identfication
  • 7635475
  • 10610730
• RefSeq identity
  • NM_006289
• Classification
  • FERM domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000019874

Gene info

• Identity
  HGNC:13519
• Gene
  TLNRD1
• Long gene name
  talin rod domain containing 1
• Synonyms gene
  • MESDC1
• Synonyms gene name
  • mesoderm development candidate 1
• Synonyms
  • MGC99595
• GenBank acession
  • AY007810
• Locus
  15q25.1
• Discovery year
  2000-09-25
• Entrez gene record
  59274
• Pubmed identfication
  • 11247670
  • 20610383
• RefSeq identity
  • NM_022566
• VEGA ID
  OTTHUMG00000144185

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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