SUV39H1 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-5708R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  SUV39H1 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-SUV39H1 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SUV39H1
• Specificity
  This is a highly specific antibody against SUV39H1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Histone-lysine N-methyltransferase SUV39H1
• Gene ID Number
  6839
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as repression of MYOD1-stimulated differentiation, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, BMP-induced repression, repression of switch recombination to IgA and regulation of telomere length. Component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  H3 K9 HMTase; H3 K9 HMTase1; H3-K9-HMTase 1; Histone H3 K9 methylation; Histone H3 Lys 9 methylation; Histone H3-K9 methyltransferase 1; Histone H3-K9 methyltransferase1; Histone lysine N methyltransferase H3 lysine 9 specic 1; Histone lysine N methyltransferase, H3 lysine 9 specic 1; Histone-lysine N-methyltransferase SUV39H1; KMT1 A; Lysine N methyltransferase 1A; Lysine N-methyltransferase 1A; MG44; mIS6; Position-effect variegation 3-9 homolog; Suvar3 9 homolog 1; Suvar3-9 homolog 1; Suppressor of variegation 3 9 homolog 1 Drosophila; Suppressor of variegation 3-9 homolog 1; SUV39 H1; SUV39H; SUV39H1; SUV91_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-SUV39H1 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  SUV39H1  
• Gene symbol
  SUV39H1
• Short name
  Anti-SUV39H1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  SUV39H1 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11479
• Gene
  SUV39H1
• Long gene name
  SUV39H1 histone lysine methyltransferase
• Synonyms gene
  • SUV39H
• Synonyms gene name
  • suppressor of variegation 3-9 (Drosophila) homolog 1
  • suppressor of variegation 3-9 homolog 1 (Drosophila)
  • suppressor of variegation 3-9 homolog 1
• Synonyms
  • KMT1A
• GenBank acession
  • AF019968
• Locus
  Xp11.23
• Discovery year
  1996-04-12
• Entrez gene record
  6839
• Pubmed identfication
  • 10202156
• RefSeq identity
  • NM_003173
• Classification
  • eNoSC complex
  • SET domain containing
  • Lysine methyltransferases
• VEGA ID
  OTTHUMG00000022701
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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