STK3+STK4 Antibody, ALEXA FLUOR 555
-
Catalog numberbs-7599R-A555
-
PricePlease ask
-
Size100ul
-
-
Long nameSTK3+STK4 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
-
Also known asAnti-STK3+STK4 PAb ALEXA FLUOR 555
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 555
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenSTK3+STK4
-
SpecificityThis is a highly specific antibody against STK3+STK4.
-
ModificationUnmodified
-
Modification SiteNone
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
Immunogen range110-150/491
-
Subcellular locationHelical
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human STK3
-
Gene ID Number6788, 6789
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenStress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission553nm/568nm
-
SynonymsSerine/threonine-protein kinase 3; Mammalian STE20-like protein kinase 2; MST-2; STE20-like kinase MST2; Serine/threonine-protein kinase Krs-1; Serine/threonine-protein kinase 4; Mammalian STE20-like protein kinase 1; MST-1; STE20-like kinase MST1; Serine/threonine-protein kinase Krs-2
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor, ALEXA FLUOR 555
-
French translationanticorps
-
Gene target
-
Gene symbolSTK4-DT, STK3, STK4, STK24
-
Short nameAnti-STK3+STK4
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 555
-
Alternative nameSTK3+STK4 Polyclonal Antibody, ALEXA FLUOR 555
-
Alternative techniqueantibodies
-
Alternative to gene targetserine/threonine kinase 3, KRS1 and MST2, STK3 and IDBG-30072 and ENSG00000104375 and 6788, transferase activity, nuclei, Stk3 and IDBG-134139 and ENSMUSG00000022329 and 56274, STK3 and IDBG-645151 and ENSBTAG00000026234 and 533815
-
Gene info
-
Identity
-
Gene
-
Long gene nameSTK4 divergent transcript
-
Synonyms gene
-
Synonyms gene name
- STK4 antisense RNA 1 (non-protein coding)
- STK4 antisense RNA 1
- STK4 antisense RNA 1 (head to head)
-
Locus
-
Discovery year2012-03-09
-
Entrez gene record
-
RefSeq identity
-
Classification
- Divergent transcripts
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameserine/threonine kinase 3
-
Synonyms gene name
- serine/threonine kinase 3 (Ste20, yeast homolog)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1997-10-09
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameserine/threonine kinase 4
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1997-10-09
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameserine/threonine kinase 24
-
Synonyms gene name
- serine/threonine kinase 24 (Ste20, yeast homolog)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2000-02-11
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- STRIPAK complex
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data