SP1 (Thr453) Antibody, ALEXA FLUOR 555
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Catalog number
bs-12412R-A555
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Price
Please ask
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Size
100ul
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Long name
SP1 (Thr453) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
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Also known as
Anti-SP1 Thr453 PAb ALEXA FLUOR 555
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 555
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
SP1 Thr453
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Specificity
This is a highly specific antibody against SP1 Thr453.
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Modification
Phosphorylation
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Modification Site
Thr453
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic phosphopeptide derived from human TSFP1 around the phosphorylation site of Thr453
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Gene ID Number
6667
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Sp1 is a sequence-specific transcription factor that recognizes GGGGCGGGGC and closely related sequences, which are often referred to as GC boxes. Sp1 was initially identified as a HeLa cell-derived factor that selectively activates in vitro transcription from the SV40 promoter and binds to the multiple GC boxes in the 21-bp repeated elements in SV40. The sequence specificity of DNA binding is conferred by Zn (II) fingers, whereas a different region of Sp1 appears to regulate the affinity of DNA binding. Sp1 belongs to a subgroup of transcription factors that are phosphorylated upon binding to promoter sequences. Evidence suggests that the early growth response gene, Erg-1 (also known as Zif268 or NGF1-A) (7), may downregulate certain mammalian gene promoters by competing with Sp1 for binding to an overlapping binding motif. The gene encoding human Sp1 maps to chromosome 12q13.1.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
553nm/568nm
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Synonyms
SP1 Thr453; SP1 T453; p-SP1 phospho T453; p-TSFP1 phospho T453; Sp1 transcription factor isoform a; TSFP1; TSFP 1; Specicity protein 1; Transcription factor Sp1; SP 1; SP1; Sp1 transcription factor; SP1_HUMAN.
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Properties
For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR 555
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French translation
anticorps
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Gene target
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Gene symbol
SP1, PRSS55, ST14
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Short name
Anti-SP1 Thr453
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 555
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Alternative name
SP1 (Thr453) Polyclonal Antibody, ALEXA FLUOR 555
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
Sp1 transcription factor
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1991-06-04
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Entrez gene record
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Pubmed identfication
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Classification
- Sp transcription factors
- Zinc fingers C2H2-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
serine protease 55
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2010-04-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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