RPS6KB1(Ser434) Antibody, ALEXA FLUOR 488
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Catalog numberbs-5671R-A488
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Price:
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Size100ul
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Long nameRPS6KB1(Ser434) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
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Also known asAnti-RPS6KB1 Ser434 PAb ALEXA FLUOR 488
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 488
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenRPS6KB1 Ser434
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SpecificityThis is a highly specific antibody against RPS6KB1 Ser434.
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ModificationPhosphorylation
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Modification SiteSer434
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from human RPS6KB1 around the phosphorylation site of Ser434
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Gene ID Number6198
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenThis gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission499nm/519nm
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SynonymsRPS6KB1 phospho S434; RPS6KB1 phospho Ser434; p-RPS6KB1 Ser434; RPS6KB1; PS6K; S6K; S6K1; STK14A; p70S6K-alpha; p70-S6K; p70-alpha; ribosomal protein S6 kinase; 70kDa; p70 S6 Kinase; P70 Beta1; KS6B1_HUMAN; Ribosomal protein S6 kinase beta-1; S6K-beta-1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-RPS6KB1 Ser434 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor
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French translationanticorps
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Gene target
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Gene symbolRPS6KB1
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Short nameAnti-RPS6KB1 Ser434
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 488
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Alternative nameRPS6KB1(Ser434) Polyclonal Antibody, ALEXA FLUOR 488
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Alternative techniqueantibodies
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Alternative to gene targetribosomal protein S6 kinase, 70kDa, polypeptide 1, p70 S6KA and p70-alpha and p70-S6K and p70(S6K)-alpha and PS6K and S6K and S6K-beta-1 and S6K1 and STK14A, RPS6KB1 and IDBG-61938 and ENSG00000108443 and 6198, transferase activity, nuclei, Rps6kb1 and IDBG-206895 and ENSMUSG00000020516 and 72508, RPS6KB1 and IDBG-629797 and ENSBTAG00000016851 and 404181
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Gene info
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Identity
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Gene
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Long gene nameribosomal protein S6 kinase B1
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Synonyms gene
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Synonyms gene name
- ribosomal protein S6 kinase, 70kD, polypeptide 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-07-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- AGC family kinases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data