RASGRF1 (Ser929) Antibody, ALEXA FLUOR 488
#
-
Catalog numberbs-5683R-A488
-
Price:
-
Size100ul
-
-
Long nameRASGRF1 (Ser929) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
-
Also known asAnti-RASGRF1 Ser929 PAb ALEXA FLUOR 488
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 488
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenRASGRF1 Ser929
-
SpecificityThis is a highly specific antibody against RASGRF1 Ser929.
-
ModificationPhosphorylation
-
Modification SiteSer929
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
SourceKLH conjugated synthetic phosphopeptide derived from human RasGRF1 around the phosphorylation site of Ser929
-
Gene ID Number5923
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenThe protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission499nm/519nm
-
SynonymsRASGRF1phospho S929; RASGRF1phospho Ser929; p-RASGRF1S929; p-RASGRF1Ser929; CDC25; CDC25L; GNRP; GRF1; GRF55; Guanine nucleotide exchange factor; Guanine nucleotide releasing factor 55 kD; Guanine nucleotide releasing protein; HGRF55; PP13187; Ras protein specic guanine nucleotide releasing factor 1; Ras specic guanine nucleotide releasing factor; Ras specic guanine nucleotide releasing factor CDC25 homolog; Ras specic nucleotide exchange factor CDC25.
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-RASGRF1 Ser929 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor
-
French translationanticorps
-
Gene target
-
Gene symbolRASGRF1
-
Short nameAnti-RASGRF1 Ser929
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 488
-
Alternative nameRASGRF1 (Ser929) Polyclonal Antibody, ALEXA FLUOR 488
-
Alternative techniqueantibodies
-
Alternative to gene targetRas protein-specific guanine nucleotide-releasing factor 1, CDC25 and CDC25L and GNRP and GRF1 and GRF55 and H-GRF55 and PP13187 and ras-GRF1, RASGRF1 and IDBG-25346 and ENSG00000058335 and 5923, glutamate receptor binding, Plasma membranes, Rasgrf1 and IDBG-190479 and ENSMUSG00000032356 and 19417, RASGRF1 and IDBG-630181 and ENSBTAG00000019940 and 520039
-
Gene info
-
Identity
-
Gene
-
Long gene nameRas protein specific guanine nucleotide releasing factor 1
-
Synonyms gene
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1994-02-11
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Dbl family Rho GEFs
- Pleckstrin homology domain containing
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data