Protocadherin 10 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-13723R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  Protocadherin 10 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-Protocadherin 10 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Protocadherin 10
• Specificity
  This is a highly specific antibody against Protocadherin 10.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  25-75/1040
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PCDH10
• Gene ID Number
  57575
• Swiss Prot
  Q9P2E7
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH10 (protocadherin 10), also known as PCDH19 or OL-PCDH, is a 1,040 amino acid single-pass type I membrane protein that contains six cadherin domains and one transmembrane domain. Expressed at moderate levels in brain, ovary and testis and present at lower levels in all other tissues, PCDH10 functions as a calcium-dependent cell-adhesion protein that may function as a tumor suppressor. When underexpressed, PCDH10 is associated with the progression of various carcinomas, including gastric cancer.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  PCDH19; OL-PCDH; Protocadherin-1; PCDH1; KIAA14
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Protocadherin 10 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  Protocadherin  
• Gene symbol
  PCDHB10, PCDH10, PCDHGA10
• Short name
  Anti-Protocadherin 10
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  Protocadherin 10 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8681
• Gene
  PCDHB10
• Long gene name
  protocadherin beta 10
• GenBank acession
  • AF152489
• Locus
  5q31.3
• Discovery year
  2000-06-28
• Entrez gene record
  56126
• Pubmed identfication
  • 10380929
• RefSeq identity
  • NM_018930
• Classification
  • Clustered protocadherins
• VEGA ID
  OTTHUMG00000129626

Gene info

• Identity
  HGNC:13404
• Gene
  PCDH10
• Long gene name
  protocadherin 10
• Synonyms
  • OL-PCDH
  • KIAA1400
• GenBank acession
  • AB037821
• Locus
  4q28.3
• Discovery year
  2001-06-25
• Entrez gene record
  57575
• Pubmed identfication
  • 10835267
• RefSeq identity
  • NM_032961
• Classification
  • Non-clustered protocadherins
• VEGA ID
  OTTHUMG00000161301

Gene info

• Identity
  HGNC:8697
• Gene
  PCDHGA10
• Long gene name
  protocadherin gamma subfamily A, 10
• Synonyms
  • PCDH-GAMMA-A10
• Locus
  5q31.3
• Discovery year
  2000-06-28
• Entrez gene record
  56106
• Pubmed identfication
  • 10380929
• RefSeq identity
  • NM_018913
• Classification
  • Clustered protocadherins
• VEGA ID
  OTTHUMG00000163688

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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