PDZ RHOGEF/GTRAP48 Antibody, ALEXA FLUOR 488
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Catalog numberbs-10157R-A488
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PricePlease ask
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Size100ul
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Long namePDZ RHOGEF/GTRAP48 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
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Also known asAnti-PDZ RHOGEF/GTRAP48 PAb ALEXA FLUOR 488
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 488
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenPDZ RHOGEF/GTRAP48
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SpecificityThis is a highly specific antibody against PDZ RHOGEF/GTRAP48.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationCytoplasm
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDZ RHOGEF/GTRAP48
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenRho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission499nm/519nm
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SynonymsPDZ-RhoGEF; ARHGB_HUMAN; ARHGEF 11; ARHGEF11; DKFZp667F1223; Glutamate transporter EAAT4 associated protein 48; GTRAP 48; GTRAP48; PDZ RhoGEF; Rho guanine exchange factor GEF 11; Rho guanine nucleotide exchange factor GEF 11; Rho guanine nucleotide exchange factor 11; RhoA specic guanine nucleotide exchange factor; RhoGEF glutamate transport modulator.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-PDZ RHOGEF/GTRAP48 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor
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French translationanticorps
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Gene target
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Gene symbolARHGEF11, ARHGEF17, ARHGEF1, RGS3, ARHGEF15, ARHGEF18, RAPGEF6, RAPGEF2, USH1C
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Short nameAnti-PDZ RHOGEF/GTRAP48
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 488
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Alternative namePDZ RHOGEF/GTRAP48 Polyclonal Antibody, ALEXA FLUOR 488
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameRho guanine nucleotide exchange factor 11
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Synonyms gene name
- Rho guanine nucleotide exchange factor (GEF) 11
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-02-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
- Dbl family Rho GEFs
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRho guanine nucleotide exchange factor 17
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Synonyms gene name
- Rho guanine nucleotide exchange factor (GEF) 17
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-09-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Dbl family Rho GEFs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRho guanine nucleotide exchange factor 1
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Synonyms gene name
- Rho guanine nucleotide exchange factor (GEF) 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-03-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Dbl family Rho GEFs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameregulator of G protein signaling 3
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Synonyms gene name
- regulator of G-protein signalling 3
- regulator of G-protein signaling 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Regulators of G-protein signaling
- C2 domain containing
- PDZ domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRho guanine nucleotide exchange factor 15
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Synonyms gene name
- Rho guanine nucleotide exchange factor (GEF) 15
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-04-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Dbl family Rho GEFs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRho/Rac guanine nucleotide exchange factor 18
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Synonyms gene name
- rho/rac guanine nucleotide exchange factor (GEF) 18
- Rho/Rac guanine nucleotide exchange factor (GEF) 18
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-01-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Dbl family Rho GEFs
- Pleckstrin homology domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRap guanine nucleotide exchange factor 6
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Synonyms gene
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Synonyms gene name
- PDZ domain containing guanine nucleotide exchange factor (GEF) 2
- Rap guanine nucleotide exchange factor (GEF) 6
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-09-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRap guanine nucleotide exchange factor 2
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Synonyms gene
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Synonyms gene name
- PDZ domain containing guanine nucleotide exchange factor (GEF) 1
- Rap guanine nucleotide exchange factor (GEF) 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-05-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- PDZ domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameUSH1 protein network component harmonin
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Synonyms gene
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Synonyms gene name
- deafness, autosomal recessive 18
- Usher syndrome 1C (autosomal recessive, severe)
- Usher syndrome 1C
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-06-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data