NARF Antibody, ALEXA FLUOR 488

• Catalog number
  bs-11173R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  NARF Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-NARF PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  NARF
• Specificity
  This is a highly specific antibody against NARF.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NARF
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Prenylation and methylation are two forms of protein modification, both of which are important for a variety of functions, including membrane attachment, protein-protein interactions and signaling events. NARF (nuclear prelamin A recognition factor), also known as IOP2, is a 456 amino acid nuclear protein that belongs to the NARF family. Expressed ubiquitously with highest expression in heart, skeletal muscle and brain, NARF binds to the C-terminal end of prenylated prelamin A and may be a member of a prelamin A-containing endoprotease complex. Additionally, via its association with prelamin A, NARF may be involved in heterochromatin organization. NARF is expressed as three isoforms due to alternative splicing events and, upon DNA damage, may be phosphorylated by ATM or ATR.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  DKFZp434G0420; FLJ10067; GC17P078009; IOP2; Iron only hydrogenase like protein 2; Nuclear prelamin A recognition factor; Prenyl dependent prelamin A binding NARF_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-NARF has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  NARF  
• Gene symbol
  NARF-IT1, NARF-AS2, RNF138, NARF-AS1, NARF
• Short name
  Anti-NARF
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  NARF Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:43651
• Gene
  NARF-IT1
• Long gene name
  NARF intronic transcript 1
• Synonyms gene
  • NARF-OT1
• Synonyms gene name
  • NARF overlapping transcript 1 (non-protein coding)
  • NARF intronic transcript 1 (non-protein coding)
• Locus
  17q25.3
• Discovery year
  2011-12-19
• Entrez gene record
  100506001
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000178846

Gene info

• Identity
  HGNC:55327
• Gene
  NARF-AS2
• Long gene name
  NARF antisense RNA 2
• Locus
  17q25.3
• Discovery year
  2020-10-21
• Entrez gene record
  105371941
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:17765
• Gene
  RNF138
• Long gene name
  ring finger protein 138
• Synonyms gene name
  • ring finger protein 138, E3 ubiquitin protein ligase
• Synonyms
  • STRIN
  • NARF
• Synonyms name
  • nemo-like kinase associated ring finger protein
• GenBank acession
  • AF162680
• Locus
  18q12.1
• Discovery year
  2003-05-21
• Entrez gene record
  51444
• Pubmed identfication
  • 22155992
  • 16714285
• RefSeq identity
  • NM_016271
• Classification
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000132265

Gene info

• Identity
  HGNC:53622
• Gene
  NARF-AS1
• Long gene name
  NARF antisense RNA 1
• Synonyms
  • ENST00000582249.1
• GenBank acession
  • BQ877948
• Locus
  17q25.3
• Discovery year
  2017-07-26
• Pubmed identfication
  • 28732507
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:29916
• Gene
  NARF
• Long gene name
  nuclear prelamin A recognition factor
• Synonyms
  • FLJ10067
  • DKFZp434G0420
  • IOP2
• Synonyms name
  • iron-only hydrogenase-like protein 2
• GenBank acession
  • BC000438
• Locus
  17q25.3
• Discovery year
  2005-11-22
• Entrez gene record
  26502
• Pubmed identfication
  • 10514485
  • 15667261
• RefSeq identity
  • NM_031968
• VEGA ID
  OTTHUMG00000178844

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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