Leptin Antibody, ALEXA FLUOR 647

• Catalog number
  bs-4604R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  Leptin Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-Leptin PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Leptin
• Specificity
  This is a highly specific antibody against Leptin.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Leptin.
• Gene ID Number
  3952
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Leptin, the product of the ob (obese) gene, is a 16kD protein consisting of 146 amino acid residues. Leptin is produced in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and regulation of body weight. It targets the central nervous system, particularly hypothalamus, affecting food intake. Leptin levels are high in most obese individuals. Studies have shown that it may also influence reproductive function.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  LEP; Leptin Murine Obesity Homolog; Leptin Precursor Obesity Factor; OB; Obese Protein; Obesity; Obesity factor; Obesity homolog mouse; Obesity Murine Homolog Leptin; OBS.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-Leptin exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• Gene
  Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
• French translation
  anticorps

• Gene target
  Leptin  
• Gene symbol
  LEP, LEPR, LEPROT
• Short name
  Anti-Leptin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  Leptin Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6553
• Gene
  LEP
• Long gene name
  leptin
• Synonyms gene
  • OBS
  • OB
• Synonyms gene name
  • leptin (murine obesity homolog)
  • leptin (obesity homolog, mouse)
• Locus
  7q32.1
• Discovery year
  1993-01-26
• Entrez gene record
  3952
• Pubmed identfication
  • 1686014
  • 16932309
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000157564

Gene info

• Identity
  HGNC:6554
• Gene
  LEPR
• Long gene name
  leptin receptor
• Synonyms
  • OBR
  • CD295
• GenBank acession
  • U43168
• Locus
  1p31.3
• Discovery year
  1996-05-09
• Entrez gene record
  3953
• Pubmed identfication
  • 8548812
  • 8812446
• RefSeq identity
  • NM_002303
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000009115
• Locus Specific Databases
  • LRG_283

Gene info

• Identity
  HGNC:29477
• Gene
  LEPROT
• Long gene name
  leptin receptor overlapping transcript
• Synonyms
  • OBRGRP
  • OB-RGRP
  • VPS55
  • FLJ90360
• Synonyms name
  • leptin receptor gene related protein
  • endospanin-1
  • endospanin
• GenBank acession
  • Y12670
• Locus
  1p31.3
• Discovery year
  2004-11-16
• Entrez gene record
  54741
• Pubmed identfication
  • 9207021
  • 21454707
• RefSeq identity
  • NM_017526
• VEGA ID
  OTTHUMG00000009065

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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