HEXO Antibody, ALEXA FLUOR 647

• Catalog number
  bs-15470R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  HEXO Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-HEXO PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  HEXO
• Specificity
  This is a highly specific antibody against HEXO.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  75-125/349
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HEXO
• Gene ID Number
  90459
• Swiss Prot
  Q8IV48
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  HEXO; THEX1; 3'HEXO; 3'-5' exoribonuclease 1; 3'-5' exonuclease ERI1; Eri-1 homolog; Histone mRNA 3'-end-specific exoribonuclease; Histone mRNA 3'-exonuclease 1; Protein 3'hExo; ERI1; 3'EXO
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-HEXO exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  HEXO  
• Gene symbol
  ERI1
• Short name
  Anti-HEXO
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  HEXO Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:23994
• Gene
  ERI1
• Long gene name
  exoribonuclease 1
• Synonyms gene
  • THEX1
• Synonyms gene name
  • three prime histone mRNA exonuclease 1
• Synonyms
  • 3'HEXO
• Synonyms name
  • exoribonuclease 1
  • enhanced RNAi three prime mRNA exonuclease homolog 1 (C.elegans)
• GenBank acession
  • BC035279
• Locus
  8p23.1
• Discovery year
  2005-05-24
• Entrez gene record
  90459
• Pubmed identfication
  • 14536070
• RefSeq identity
  • NM_153332
• Classification
  • MicroRNA protein coding host genes
  • Exonucleases
• VEGA ID
  OTTHUMG00000129328

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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