GRIK2/GLR6 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-12006R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  GRIK2/GLR6 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-GRIK2/GLR6 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  GRIK2/GLR6
• Specificity
  This is a highly specific antibody against GRIK2/GLR6.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GRIK2/GLR6
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  CSNB 1B; DKFZp686H1993; EAA4; Excitatory amino acid receptor 4; G protein coupled receptor family C group 1 member F; GLR 6; GLR6; GLUR 6; GluR-6; GLUR6; Glutamate receptor 6; Glutamate receptor; Glutamate receptor ionotropic kainate 2; Gprc 1f; Gprc1f; GRIK 2; GRIK2; GRIK2 protein; GRIK2_HUMAN; GRM 6; ionotropic kainate 2.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-GRIK2/GLR6 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  GRIK2/GLR6  
• Gene symbol
  GRIK5, GRIK2
• Short name
  Anti-GRIK2/GLR6
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  GRIK2/GLR6 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  glutamate receptor, ionotropic, kainate 2, EAA4 and GLR6 and GluK2 and GLUK6 and GLUR6 and MRT6, GRIK2 and IDBG-94705 and ENSG00000164418 and 2898, protein homodimerization activity, Cell surfaces, Grik2 and IDBG-149430 and ENSMUSG00000056073 and 14806, GRIK2 and IDBG-631973 and ENSBTAG00000033153 and 615226

Gene info

• Identity
  HGNC:4583
• Gene
  GRIK5
• Long gene name
  glutamate ionotropic receptor kainate type subunit 5
• Synonyms gene
  • GRIK2
• Synonyms gene name
  • glutamate receptor, ionotropic, kainate 5
• Synonyms
  • GluK5
  • KA2
• Locus
  19q13.2
• Discovery year
  1993-10-21
• Entrez gene record
  2901
• Pubmed identfication
  • 7527545
• Classification
  • Glutamate ionotropic receptor kainate type subunits
• VEGA ID
  OTTHUMG00000044573

Gene info

• Identity
  HGNC:4580
• Gene
  GRIK2
• Long gene name
  glutamate ionotropic receptor kainate type subunit 2
• Synonyms gene
  • GLUR6
• Synonyms gene name
  • glutamate receptor, ionotropic, kainate 2
• Synonyms
  • GluK2
  • MRT6
• Locus
  6q16.3
• Discovery year
  1992-02-26
• Entrez gene record
  2898
• Pubmed identfication
  • 8034316
• Classification
  • Glutamate ionotropic receptor kainate type subunits
• VEGA ID
  OTTHUMG00000016328

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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