FYB/ADAP Antibody, ALEXA FLUOR 647

• Catalog number
  bs-13236R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  FYB/ADAP Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-FYB/ADAP PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  FYB/ADAP
• Specificity
  This is a highly specific antibody against FYB/ADAP.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FYB/ADAP
• Gene ID Number
  2533
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Fyb (Fyn binding protein) and the anchoring proteins SKAP55 (src kinase-associated phosphoprotein) and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn (1–3). SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells (1–3). SKAP55 contains an amino-terminal pleckstrin homology domain and a carboxy-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i.e. RKxxYxxY) (4,5). SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain (1,2). SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation (6). The human Fyb gene maps to chromosome 5p13.1 and encodes a 783 amino acid protein (7).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  ADAP; Adhesion and degranulation promoting adaptor protein; FYB 120/130; Fyb; FYB-120/130; FYB_HUMAN; FYN binding protein; FYN T binding protein; FYN-binding protein; FYN-T-binding protein; p120/p130; PRO0823; SLAP 130; SLAP-130; SLAP130; SLP 76 associated phosphoprotein; SLP-76-associated phosphoprotein; SLP76 associated phosphoprotein.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-FYB/ADAP exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  FYB/ADAP  
• Gene symbol
  FYB1, AGPS
• Short name
  Anti-FYB/ADAP
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  FYB/ADAP Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  FYN binding protein, ADAP and PRO0823 and SLAP-130, FYB and IDBG-17782 and ENSG00000082074 and 2533, protein complex binding, nuclei, Fyb and IDBG-128115 and ENSMUSG00000022148 and 23880, FYB and IDBG-629944 and ENSBTAG00000001492 and 535347

Gene info

• Identity
  HGNC:4036
• Gene
  FYB1
• Long gene name
  FYN binding protein 1
• Synonyms gene
  • FYB
• Synonyms gene name
  • FYN-binding protein (FYB-120/130)
  • FYN binding protein
• Synonyms
  • SLAP-130
  • FYB-120/130
  • ADAP
• Synonyms name
  • adhesion and degranulation promoting adaptor protein
• GenBank acession
  • U93049
• Locus
  5p13.1
• Discovery year
  1998-04-22
• Entrez gene record
  2533
• Pubmed identfication
  • 9115214
  • 9207119
• RefSeq identity
  • NM_001465
• VEGA ID
  OTTHUMG00000162071
• Locus Specific Databases
  • LRG_1351

Gene info

• Identity
  HGNC:327
• Gene
  AGPS
• Long gene name
  alkylglycerone phosphate synthase
• Synonyms
  • ADHAPS
  • ADAS
  • ALDHPSY
  • ADPS
  • ADAP-S
• GenBank acession
  • Y09443
• Locus
  2q31.2
• Discovery year
  1998-10-14
• Entrez gene record
  8540
• Pubmed identfication
  • 9187299
  • 9553082
• VEGA ID
  OTTHUMG00000132530

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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