EGFR (Ser768) Antibody, ALEXA FLUOR 488
#
-
Catalog numberbs-5320R-A488
-
Price:
-
Size100ul
-
-
Long nameEGFR (Ser768) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
-
Also known asAnti-EGFR Ser768 PAb ALEXA FLUOR 488
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 488
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenEGFR Ser768
-
SpecificityThis is a highly specific antibody against EGFR Ser768.
-
ModificationPhosphorylation
-
Modification SiteSer768
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
SourceKLH conjugated synthetic phosphopeptide derived from human EGFR around the phosphorylation site of Ser768
-
Gene ID Number1956
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenProtein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission499nm/519nm
-
SynonymsEGFR; Avian erythroblastic leukemia viral v erb b oncogene homolog; Avian erythroblastic leukemia viral verbb oncogene homolog; Cell growth inhibiting protein 40; Cell proliferation inducing protein 61; EGF R; EGFR; Epidermal growth factor receptor avian erythroblastic leukemia viral v erb b oncogene homolog; Epidermal growth factor receptor erythroblastic leukemia viral v erb b oncogene homolog avian; Epidermal growth factor receptor; erbb 1; Erbb; Erbb1; HER1; mENA; Oncogene ERBB; PIG61; Receptor tyrosine protein kinase ErbB 1; Receptor tyrosine protein kinase ErbB1; Urogastrone; wa2; Wa5.
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-EGFR Ser768 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor
-
French translationanticorps
-
Gene target
-
Gene symbolEGFR-AS1, EGILA, EGFR, RHBDF1
-
Short nameAnti-EGFR Ser768
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 488
-
Alternative nameEGFR (Ser768) Polyclonal Antibody, ALEXA FLUOR 488
-
Alternative techniqueantibodies
-
Alternative to gene targetepidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217
-
Gene info
-
Identity
-
Gene
-
Long gene nameEGFR antisense RNA 1
-
Locus
-
Discovery year2012-11-06
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Antisense RNAs
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameEGFR interacting lncRNA
-
Synonyms
-
Locus
-
Discovery year2019-09-27
-
Pubmed identfication
-
Classification
- Long non-coding RNAs with non-systematic symbols
Gene info
-
Identity
-
Gene
-
Long gene nameepidermal growth factor receptor
-
Synonyms gene
-
Synonyms gene name
- epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Erb-b2 receptor tyrosine kinases
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene namerhomboid 5 homolog 1
-
Synonyms gene
-
Synonyms gene name
- chromosome 16 open reading frame 8
- rhomboid family 1 (Drosophila)
- rhomboid 5 homolog 1 (Drosophila)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-04-07
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Rhomboid family
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data