E cadherin Antibody, ALEXA FLUOR 488
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Catalog number
bs-10009R-A488
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Price
Please ask
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Size
100ul
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Long name
E cadherin Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
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Also known as
Anti-E cadherin PAb ALEXA FLUOR 488
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 488
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
E cadherin
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Specificity
This is a highly specific antibody against E cadherin.
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Modification
Unmodified
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Modification Site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen range
410-460/882
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Subcellular location
Extracellular
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human E-cadherin
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Gene ID Number
999
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Swiss Prot
P12830
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Tested applications
FCM, IF(IHC-P), IF(ICC)
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Recommended dilutions
FCM(1:20-100), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
499nm/519nm
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Synonyms
UVO; CDHE; ECAD; LCAM; Arc-1; CD324; Cadherin-1; CAM 12/8; Epithelial cadherin; E-cadherin; Uvomorulin; CDH1
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Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-E cadherin has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor
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French translation
anticorps
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Gene target
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Gene symbol
CDH1, CTNNA1
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Short name
Anti-E cadherin
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 488
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Alternative name
E cadherin Polyclonal Antibody, ALEXA FLUOR 488
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
cadherin 1
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Synonyms gene
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Synonyms gene name
- cadherin 1, type 1, E-cadherin (epithelial)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Type I classical cadherins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
catenin alpha 1
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Synonyms gene name
- catenin (cadherin-associated protein), alpha 1 (102kD)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1993-07-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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