Dystrophin Antibody, ALEXA FLUOR 647

• Catalog number
  bs-6718R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  Dystrophin Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-Dystrophin PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Dystrophin
• Specificity
  This is a highly specific antibody against Dystrophin.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dystrophin/DMD
• Gene ID Number
  1756
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.Tissue specificityExpressed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma. Expressed in brain, muscle, kidney, lung and testis. Isoform 5 is expressed in heart, brain, liver, testis and hepatoma cells. Most tissues contain transcripts of multiple isoforms, however only isoform 5 is detected in heart and liver.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  Alternative namesApo dystrophin;BMD;CMD3B;DMD;DMD_HUMAN;Duchenne muscular dystrophy protein;DXS142;DXS164;DXS206;DXS230;DXS239;DXS268;DXS269;DXS270;DXS272;Dystrophin;Muscular dystrophy Duchenne and Becker types.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-Dystrophin exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  Dystrophin  
• Gene symbol
  DRP2, DAG1, SGCB
• Short name
  Anti-Dystrophin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  Dystrophin Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3032
• Gene
  DRP2
• Long gene name
  dystrophin related protein 2
• GenBank acession
  • U43519
• Locus
  Xq22.1
• Discovery year
  1996-07-17
• Entrez gene record
  1821
• Pubmed identfication
  • 8640231
• RefSeq identity
  • NM_001939
• Classification
  • Zinc fingers ZZ-type
• VEGA ID
  OTTHUMG00000022020
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:2666
• Gene
  DAG1
• Long gene name
  dystroglycan 1
• Synonyms gene name
  • dystroglycan 1 (dystrophin-associated glycoprotein 1)
• Synonyms
  • A3a
  • 156DAG
  • AGRNR
  • DAG
• Synonyms name
  • alpha-dystroglycan
  • dystrophin-associated glycoprotein-1
  • beta-dystroglycan
• GenBank acession
  • L19711
• Locus
  3p21.31
• Discovery year
  1997-07-22
• Entrez gene record
  1605
• Pubmed identfication
  • 7774920
  • 1741056
• VEGA ID
  OTTHUMG00000156869
• Locus Specific Databases
  • Leiden Muscular Dystrophy pages
  • LRG_854

Gene info

• Identity
  HGNC:10806
• Gene
  SGCB
• Long gene name
  sarcoglycan beta
• Synonyms gene
  • LGMD2E
• Synonyms gene name
  • sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
• Synonyms
  • SGC
  • A3b
• GenBank acession
  • U29586
• Locus
  4q12
• Discovery year
  1995-01-24
• Entrez gene record
  6443
• Pubmed identfication
  • 8968749
• VEGA ID
  OTTHUMG00000128697
• Locus Specific Databases
  • Leiden Muscular Dystrophy Pages
  • Leiden Muscular Dystrophy pages
  • LRG_204

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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