Dnmt1 Antibody, ALEXA FLUOR 594
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Catalog number
bs-0678R-A594
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Price
Please ask
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Size
100ul
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Long name
Dnmt1 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
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Also known as
Anti-Dnmt1 PAb ALEXA FLUOR 594
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 594
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
Dnmt1
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Specificity
This is a highly specific antibody against Dnmt1.
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Modification
Unmodified
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Modification Site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen range
10-60/1616
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Subcellular location
Nucleus
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dnmt1
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Gene ID Number
1786
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Swiss Prot
P26358
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
590nm/617nm
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Synonyms
AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN; DNA (cytosine-5)-methyltransferase 1; Dnmt1; CXXC-type zinc finger protein 9; DNA methyltransferase HsaI; DNA MTase HsaI; M.HsaI
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Properties
For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR® 594
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Conjugated
Alexa conjugate 1
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French translation
anticorps
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Gene target
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Gene symbol
DALIR, DACOR1, DNMT1
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Short name
Anti-Dnmt1
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 594
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Alternative name
Dnmt1 Polyclonal Antibody, ALEXA FLUOR 594
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Alternative technique
antibodies
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Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
DNA methyltransferase 1
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Synonyms gene
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Synonyms gene name
- DNA (cytosine-5-)-methyltransferase 1
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Synonyms
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GenBank acession
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Locus
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Discovery year
1991-06-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- 7BS C5-cytosine DNA/RNA methyltransferases
- Zinc fingers CXXC-type
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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