DMP1 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-12359R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  DMP1 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-DMP1 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  DMP1
• Specificity
  This is a highly specific antibody against DMP1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DMP1
• Gene ID Number
  1758
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  DMP-1 is a member of the small integrin ligand N-linked glycoprotein family. It is important for the mineralization of bone and dentin. DMP-1 is expressed in bone, tooth and hypertrophic cartilage. It is synthesized by preosteoblasts and contains a large number of acidic domains. DMP-1 localizes to the nucleus of undifferentiated osteoblasts where it functions as a transcriptional regulator for osteoblast-specific gene activation and induces osteoblast differentiation. During osteoblast maturation, DMP-1 undergoes a conformational change and becomes phosphorylated by casein kinase II in response to an influx of calcium ions to the nucleus. DMP-1 is then exported to the extracellular matrix (ECM) where it regulates the nucleation of hydroxyapatite and the formation of calcified tissue. DMP-1 is proteolytically processed into N- and C-terminal fragments in the ECM of bone and dentin. The protein has also been identified in bone as a high molecular weight proteoglycan comprised of the N-terminal DMP-1 fragment and chondroitin sulfate.The loss of DMP-1 can result in hypomineralized bone.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  ARHP; ARHR; AV020965; Dentin matrix acidic phosphoprotein 1; Dentin matrix protein 1; DENTMAT; DMP 1; Dmp; MGC130441; PP; Serine rich acidic phosphoprotein; DMP1_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-DMP1 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  DMP1  
• Gene symbol
  DMP1, DMTF1
• Short name
  Anti-DMP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  DMP1 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  dentin matrix acidic phosphoprotein 1, ARHP and ARHR and DMP-1, DMP1 and IDBG-29190 and ENSG00000152592 and 1758, extracellular matrix binding, nuclei, Dmp1 and IDBG-185392 and ENSMUSG00000029307 and 13406, DMP1 and IDBG-643326 and ENSBTAG00000019132 and 281118

Gene info

• Identity
  HGNC:2932
• Gene
  DMP1
• Long gene name
  dentin matrix acidic phosphoprotein 1
• Synonyms gene name
  • dentin matrix acidic phosphoprotein
• GenBank acession
  • U34037
• Locus
  4q22.1
• Discovery year
  1995-08-10
• Entrez gene record
  1758
• Pubmed identfication
  • 8586437
  • 9177774
• Classification
  • SIBLING family
• VEGA ID
  OTTHUMG00000130598

Gene info

• Identity
  HGNC:14603
• Gene
  DMTF1
• Long gene name
  cyclin D binding myb like transcription factor 1
• Synonyms gene name
  • cyclin D binding myb-like transcription factor 1
• Synonyms
  • DMP1
  • DMTF
  • hDMP1
  • MRUL
• Synonyms name
  • cyclin D-binding Myb-like protein
• GenBank acession
  • AF084530
• Locus
  7q21.12
• Discovery year
  2001-02-28
• Entrez gene record
  9988
• Pubmed identfication
  • 10095122
  • 24958102
• RefSeq identity
  • NM_021145
• Classification
  • Myb/SANT domain containing
• VEGA ID
  OTTHUMG00000154135

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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