DC-SIGN Antibody, ALEXA FLUOR 647
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Catalog numberbs-10053R-A647
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PricePlease ask
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Size100ul
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Long nameDC-SIGN Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
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Also known asAnti-DC-SIGN PAb ALEXA FLUOR 647
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 647
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenDC-SIGN
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SpecificityThis is a highly specific antibody against DC-SIGN.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DC-SIGN/CD209
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Gene ID Number30835
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenDendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV1, HIV2 and SIV bind to DCs via DCSIGN. ICAM3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed CD299, DC-SIGNR, L-SIGN and DCSIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission650nm/665nm
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SynonymsCLEC4L; Dendritic cell-specic ICAM-3-grabbing non-integrin 1; C type lectin domain family 4 member L; CD 209; CD209; CD209 antigen; CD209 antigen-like protein A; CD209 molecule; Cd209a; CDSIGN; CIRE; DC SIGN1; DCSIGN; Dendritic cell specic ICAM 3 grabbing nonintegrin 1; Dendritic cell specic ICAM3 grabbing nonintegrin 1; Dendritic cell-specic intracellular adhesion molecules ICAM-3 grabbing non-integrin; Dengue fever, protection against, included; Dentritic Cell Specic ICAM3 Grabbing Nonintegrin; HIV GP120 Binding Protein; MGC129965; MGC130443; SIGN-R1; SIGNR5; CD209_HUMAN.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-DC-SIGN exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 647
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French translationanticorps
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Gene target
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Gene symbolCD209, CLEC4M, UBTD2, WFDC21P, TSPAN14, DCSTAMP, DCX, LAMP3, PDCD1LG2, CCL18
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Short nameAnti-DC-SIGN
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 647
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Alternative nameDC-SIGN Polyclonal Antibody, ALEXA FLUOR 647
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameCD209 molecule
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Synonyms gene name
- CD209 antigen
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-07-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
- C-type lectin domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-type lectin domain family 4 member M
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Synonyms gene
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Synonyms gene name
- CD299 antigen
- C-type lectin domain family 4, member M
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-09-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameubiquitin domain containing 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameWAP four-disulfide core domain 21, pseudogene
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Synonyms
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Synonyms name
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Locus
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Discovery year2014-06-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametetraspanin 14
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Synonyms gene
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Synonyms gene name
- transmembrane 4 superfamily member 14
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-10-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tetraspanins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedendrocyte expressed seven transmembrane protein
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Synonyms gene
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Synonyms gene name
- transmembrane 7 superfamily member 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-06-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedoublecortin
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Synonyms gene name
- doublecortex; lissencephaly, X-linked (doublecortin)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-03-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Doublecortin superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelysosomal associated membrane protein 3
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Synonyms gene name
- lysosomal-associated membrane protein 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-29
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Entrez gene record
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Pubmed identfication
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Classification
- Lysosome associated membrane proteins
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprogrammed cell death 1 ligand 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-11-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- B7 family
- CD molecules
- Immunoglobulin like domain containing
- Receptor ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine ligand 18
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Synonyms gene
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Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated
- chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
- chemokine (C-C motif) ligand 18
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-01-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chemokine ligands
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data