CRF Antibody, ALEXA FLUOR 488

• Catalog number
  bs-0246R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  CRF Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-CRF PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CRF
• Specificity
  This is a highly specific antibody against CRF.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CRF
• Gene ID Number
  1392
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010].
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  Corticoliberin; Corticoliberin precursor; Corticotropin releasing factor; Corticotropin releasing hormone; Corticotropin releasing hormone deficiency included; crf; crh; crh deficiency included; corticoliberin preproprotein; CRF_HUMAN; Corticotropin-releasing factor; CRF; CRH; Corticotropin-releasing hormone.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-CRF has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  CRF  
• Gene symbol
  CRHR2, CRH, CRHBP, CRHR1, C1QL1
• Short name
  Anti-CRF
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  CRF Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2358
• Gene
  CRHR2
• Long gene name
  corticotropin releasing hormone receptor 2
• Synonyms
  • CRF2
  • CRF-RB
  • HM-CRF
• Locus
  7p14.3
• Discovery year
  1996-12-18
• Entrez gene record
  1395
• Pubmed identfication
  • 8536644
• Classification
  • Corticotropin releasing hormone receptors
• VEGA ID
  OTTHUMG00000023218

Gene info

• Identity
  HGNC:2355
• Gene
  CRH
• Long gene name
  corticotropin releasing hormone
• Synonyms
  • CRF
  • CRH1
• Synonyms name
  • corticotropin-releasing factor
  • corticoliberin
• Locus
  8q13.1
• Discovery year
  1988-08-31
• Entrez gene record
  1392
• Pubmed identfication
  • 25521515
• RefSeq identity
  • NM_000756
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000164474

Gene info

• Identity
  HGNC:2356
• Gene
  CRHBP
• Long gene name
  corticotropin releasing hormone binding protein
• Synonyms gene name
  • corticotropin releasing hormone-binding protein
• Synonyms
  • CRF-BP
  • CRFBP
• GenBank acession
  • X58022
• Locus
  5q13.3
• Discovery year
  1991-08-07
• Entrez gene record
  1393
• Pubmed identfication
  • 8198617
• RefSeq identity
  • NM_001882
• VEGA ID
  OTTHUMG00000102133

Gene info

• Identity
  HGNC:2357
• Gene
  CRHR1
• Long gene name
  corticotropin releasing hormone receptor 1
• Synonyms gene
  • CRHR
• Synonyms
  • CRF-R
  • CRF1
• Synonyms name
  • corticotropin-releasing factor receptor
• GenBank acession
  • L23332
• Locus
  17q21.31
• Discovery year
  1993-12-13
• Entrez gene record
  1394
• Pubmed identfication
  • 7590738
• Classification
  • Corticotropin releasing hormone receptors
• VEGA ID
  OTTHUMG00000178271

Gene info

• Identity
  HGNC:24182
• Gene
  C1QL1
• Long gene name
  complement C1q like 1
• Synonyms gene name
  • complement component 1, q subcomponent-like 1
• Synonyms
  • CRF
  • C1QRF
  • C1QTNF14
  • CTRP14
• GenBank acession
  • AF410771
• Locus
  17q21.31
• Discovery year
  2004-05-06
• Entrez gene record
  10882
• Pubmed identfication
  • 9878755
• RefSeq identity
  • NM_006688
• Classification
  • C1q and TNF related
• VEGA ID
  OTTHUMG00000162944

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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