CPB2 Antibody, ALEXA FLUOR 647
-
Catalog number
bs-7547R-A647
-
Price
Please ask
-
Size
100ul
-
-
Long name
CPB2 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
-
Also known as
Anti-CPB2 PAb ALEXA FLUOR 647
-
Category
Conjugated Primary Antibodies
-
Conjugated with
ALEXA FLUOR® 647
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
CPB2
-
Specificity
This is a highly specific antibody against CPB2.
-
Modification
Unmodified
-
Modification Site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CPB2
-
Gene ID Number
1361
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigen
This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues. It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues; pI 5.0). Being activated by thrombin-thrombomodulin complex during blood coagulation, it exerts carboxypeptidase activity. Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, which is necessary for plasminogen binding to fibrin. This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot. The concentration in plasma of healthy people is 5-10 ug/ml. High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease. Elevated concentration in blood is considered as a risk factor for venous thrombosis. A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, and decreased levels are found in chronic liver disease.
-
Purification
Purified by Protein A.
-
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission
650nm/665nm
-
Synonyms
Carboxypeptidase B like protein; Carboxypeptidase U; CarboxypeptidaseB2; Carboxypeptidase B2; CarboxypeptidaseU; CP B2; CPB 2; CPB2; CPU; PCPB; Plasma carboxypeptidase B; Plasma carboxypeptidase B2; Procarboxypeptidase B; Procarboxypeptidase R; Procarboxypeptidase U; TAFI; Thrombin activable fibrinolysis inhibitor; Thrombin activatable fibrinolysis inhibitor.
-
Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-CPB2 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugation
Alexa Fluor, ALEXA FLUOR 647
-
French translation
anticorps
-
Gene target
-
Gene symbol
CPB2-AS1, CPB2
-
Short name
Anti-CPB2
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Immunoglobulin G (IgG)
-
Label
ALEXA FLUOR 647
-
Alternative name
CPB2 Polyclonal Antibody, ALEXA FLUOR 647
-
Alternative technique
antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene name
CPB2 antisense RNA 1
-
Synonyms gene name
- CPB2 antisense RNA 1 (non-protein coding)
-
Locus
-
Discovery year
2011-04-08
-
Entrez gene record
-
Classification
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
carboxypeptidase B2
-
Synonyms gene name
- carboxypeptidase B2 (plasma, carboxypeptidase U)
- carboxypeptidase B2 (plasma)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1992-04-10
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products