Claudin 1 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-1428R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  Claudin 1 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-Claudin 1 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Claudin 1
• Specificity
  This is a highly specific antibody against Claudin 1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  185-211/211
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic peptide derived from mouse Claudin 1
• Gene ID Number
  12737
• Swiss Prot
  O88551
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  AI596271; Claudin-1; Cldn1
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-Claudin 1 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  Claudin  
• Gene symbol
  CLDN3, CLDN1, CLDND1
• Short name
  Anti-Claudin 1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  Claudin 1 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2045
• Gene
  CLDN3
• Long gene name
  claudin 3
• Synonyms gene
  • C7orf1
  • CPETR2
• Synonyms
  • RVP1
  • CPE-R2
  • HRVP1
• Synonyms name
  • Clostridium perfringens enterotoxin receptor 2
  • ventral prostate.1-like protein
  • claudin-3
  • CPE-receptor 2
• GenBank acession
  • AF007189
• Locus
  7q11.23
• Discovery year
  1998-07-23
• Entrez gene record
  1365
• Pubmed identfication
  • 9441748
  • 9892664
• RefSeq identity
  • NM_001306
• Classification
  • Claudins
• VEGA ID
  OTTHUMG00000023424

Gene info

• Identity
  HGNC:2032
• Gene
  CLDN1
• Long gene name
  claudin 1
• Synonyms
  • SEMP1
  • ILVASC
• Synonyms name
  • senescence-associated epithelial membrane protein 1
• GenBank acession
  • AF101051
• Locus
  3q28
• Discovery year
  1998-11-19
• Entrez gene record
  9076
• Pubmed identfication
  • 10828592
  • 9892664
• RefSeq identity
  • NM_021101
• Classification
  • Claudins
• VEGA ID
  OTTHUMG00000156214

Gene info

• Identity
  HGNC:1322
• Gene
  CLDND1
• Long gene name
  claudin domain containing 1
• Synonyms gene
  • C3orf4
• Synonyms gene name
  • chromosome 3 open reading frame 4
• Synonyms
  • Z38
• GenBank acession
  • AF116664
• Locus
  3q11.2
• Discovery year
  2000-08-11
• Entrez gene record
  56650
• Pubmed identfication
  • 28247935
• RefSeq identity
  • NM_019895
• VEGA ID
  OTTHUMG00000160050

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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