Bax Antibody, ALEXA FLUOR 647
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Catalog numberbs-0127R-A647
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PricePlease ask
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Size100ul
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Long nameBax Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
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Also known asAnti-Bax PAb ALEXA FLUOR 647
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 647
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenBax
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SpecificityThis is a highly specific antibody against Bax.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range60-110/192
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Subcellular locationMitochondrion
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Bax
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Gene ID Number581
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Swiss ProtQ07812
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Tested applicationsFCM, IF(IHC-P), IF(ICC)
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Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
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CrossreactivityHuman, Mouse, Rat, Pig, Rabbit
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenAccelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission650nm/665nm
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SynonymsBCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-Bax exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 647
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French translationanticorps
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Gene target
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Gene symbolTMBIM7P, TMBIM6, TMBIM1
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Short nameAnti-Bax
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 647
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Alternative nameBax Polyclonal Antibody, ALEXA FLUOR 647
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Alternative techniqueantibodies
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Alternative to gene targetBCL2-associated X protein, BCL2L4, BAX and IDBG-61459 and ENSG00000087088 and 581, BH3 domain binding, nuclei, Bax and IDBG-183241 and ENSMUSG00000003873 and 12028, BAX and IDBG-640344 and ENSBTAG00000013340 and 100850136,280730
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Gene info
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Identity
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Gene
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Long gene nametransmembrane BAX inhibitor motif containing 7, pseudogene
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Locus
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Discovery year2013-10-09
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Entrez gene record
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Classification
- Transmembrane BAX inhibitor motif containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametransmembrane BAX inhibitor motif containing 6
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Synonyms gene
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Synonyms gene name
- testis enhanced gene transcript
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1994-08-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Transmembrane BAX inhibitor motif containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametransmembrane BAX inhibitor motif containing 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-08-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Transmembrane BAX inhibitor motif containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data