Argonaute 3/eIF2C3 Antibody, ALEXA FLUOR 555
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Catalog numberbs-12517R-A555
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PricePlease ask
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Size100ul
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Long nameArgonaute 3/eIF2C3 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
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Also known asAnti-Argonaute 3/e2C3 PAb ALEXA FLUOR 555
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 555
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenArgonaute 3/e2C3
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SpecificityThis is a highly specific antibody against Argonaute 3/e2C3.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Argonaute 3/eIF2C3
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Gene ID Number192669
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenEukaryotic translation initiation factor 2C (eIF2C) proteins (argonaute family) influence RNA interference (RNAi) as components of the RNA-inducible silencing complex (RISC) or microRNA (miRNA)-containing ribonucleoprotein particle (miRNP). Small RNAs, including small interfering RNAs (siRNAs) and miRNAs, can silence target genes through mechanisms that utilize RISC or miRNP particles. eIF2C1 (argonaute 1, AGO1, eIF2C, GERP95, Q99) and Dicer1 play a coordinated role in siRNA-mediated gene silencing. eIF2C2 (Slicer, argonaute 2, AGO2, Q10) is a RISC component that can concentrate in cytoplasmic processing bodies (P-bodies) and catalyze mRNA cleavage. Mammalian P-bodies contain mRNAs and have an association with miRNA-induced translational silencing and siRNA-induced mRNA degradation. Additional eIF2C proteins include eIF2C3 (argonaute 3, AGO3), eIF2C4 (argonaute 4, AGO4) and meIF2c5 (mouse argonaute 5).
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission553nm/568nm
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SynonymsArgonaute 3/e2C 3; 5730550L01Rik; Ago 3; Ago3; AGO3_HUMAN; argonaute 3; Argonaute3; e 2C 3; e-2C 3; e2C 3; E2c3; e2C3; E2C3 protein; Eukaryotic translation initiation factor 2C 3; Eukaryotic translation initiation factor 2C3; FLJ12765; hAgo3; MGC86946; Protein argonaute-3.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 555
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French translationanticorps
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Gene target
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Gene symbolAGO3
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Short nameAnti-Argonaute 3/e2C3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 555
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Alternative nameArgonaute 3/eIF2C3 Polyclonal Antibody, ALEXA FLUOR 555
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameargonaute RISC catalytic component 3
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Synonyms gene
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Synonyms gene name
- eukaryotic translation initiation factor 2C, 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-04-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Argonaute RISC component family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data