Anti-SNAIL + SLUG(Ser246) (Polyclonal), ALEXA Fluor 594
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Catalog numberGENTObs-11962R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptideSNAIL + SLUG Ser246
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SpecificityThis antibody reacts specifically with SNAIL + SLUG(Ser246)
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ModificationPhosphorylation
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Modification siteSer246
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsN/A
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Antigen SourceKLH conjugated synthetic phosphopeptide derived from human SNAIL around the phosphorylation site of Ser246
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Gene ID6311
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Swiss ProtN/A
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ApplicationsIF(IHC-P)
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Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
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Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationThis gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin. SLUG is involved in epithelial-mesenchymal transitions (EMT) involving E-cadherin repression which is known to play an important role in tumor progression amd neural tube formation. SLUG also has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects (referenced from Entrez gene).
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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SynonymsSNAIL + SLUG phospho S246 + S251; SNAIL + SLUG phospho Ser246 + Ser251; SNAILSer246 + SLUGSer251; dJ710H13.1; MGC10182; Neural crest transcription factor Slug; Protein sna; Protein snail homolog 1; Protein snail homolog 2; Protein snail homolog; Slug homolog zinc finger protein; Slug zinc finger protein; SLUGH; SLUGH 1; SLUGH1; SLUGH2; SNA; Sna protein; SNAH; SNAI 2; snai1; SNAI1_HUMAN; Snai2; SNAI2_HUMAN; Snail 2; Snail homolog 1 Drosophila; Snail homolog 2; Snail2; WS 2D; WS2D; Zinc finger protein SLUG; Zinc finger protein SNAI1; Zinc finger protein SNAI2.
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Also known asSNAIL + SLUG(Ser246) Polyclonal Antibody
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Other nameAnti-SNAIL + SLUG(Ser246) Polyclonal
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Gene target
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Gene symbolSNAI2, SNAI1
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Short nameAnti-SNAIL + SLUG(Ser246)
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TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameSNAIL + SLUG(Ser246) Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniquepolyclonals, antibodies
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Gene info
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Identity
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Gene
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Long gene namesnail family transcriptional repressor 2
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Synonyms gene
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Synonyms gene name
- slug homolog, zinc finger protein (chicken)
- snail homolog 2 (Drosophila)
- snail family zinc finger 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-07-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2H2-type
- SNAG transcriptional repressors
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namesnail family transcriptional repressor 1
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Synonyms gene name
- snail 1 (drosophila homolog), zinc finger protein
- snail homolog 1 (Drosophila)
- snail family zinc finger 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-07-03
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Entrez gene record
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Pubmed identfication
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Classification
- Zinc fingers C2H2-type
- SNAG transcriptional repressors
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data