Anti-SAPAP2/DLGAP2 (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-12139R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  SAPAP2/DLGAP2
• Specificity
  This antibody reacts specifically with SAPAP2/DLGAP2
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic peptide derived from human SAPAP2/DLGAP2
• Gene ID
  N/A
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP2, also known as DAP-2 (Disks large-associated protein 2) and PSD-95/SAP90-binding protein 2, is a 1054 amino acid protein that localizes to the postsynaptic membrane of neuronal cells of the brain and kidney. SAPAP2 likely acts as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP2, DLGAP2, maps to human chromosome 8. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  DAP-2; DAP2; Discs large Drosophila homolog associated protein 2; Discs large homolog associated protein 2; Disks large-associated protein 2; Dlgap2; DLGP2_HUMAN; PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2; SAPAP2; hide.
• Also known as
  SAPAP2/DLGAP2 Polyclonal Antibody
• Other name
  Anti-SAPAP2/DLGAP2 Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  SAPAP2/DLGAP2  
• Gene symbol
  DLGAP2-AS1, DLGAP2
• Short name
  Anti-SAPAP2/DLGAP2
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  SAPAP2/DLGAP2 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:50467
• Gene
  DLGAP2-AS1
• Long gene name
  DLGAP2 antisense RNA 1
• Locus
  8p23.3
• Discovery year
  2014-04-30
• Entrez gene record
  100507435
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000163600

Gene info

• Identity
  HGNC:2906
• Gene
  DLGAP2
• Long gene name
  DLG associated protein 2
• Synonyms gene
  • ERICH1-AS1
  • C8orf68
• Synonyms gene name
  • discs, large (Drosophila) homolog-associated protein 2
  • discs large homolog associated protein 2
  • ERICH1 antisense RNA 1
  • chromosome 8 open reading frame 68
  • ERICH1 antisense RNA 1 (non-protein coding)
• Synonyms
  • DAP-2
• GenBank acession
  • AB000275
• Locus
  8p23.3
• Discovery year
  1999-02-23
• Entrez gene record
  9228
• Pubmed identfication
  • 9286858
  • 10854099
• RefSeq identity
  • NM_004745
• VEGA ID
  OTTHUMG00000163599

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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