Anti-SAPAP1/DLGAP1 (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-12138R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  SAPAP1/DLGAP1
• Specificity
  This antibody reacts specifically with SAPAP1/DLGAP1
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic peptide derived from human SAPAP1/DLGAP1
• Gene ID
  N/A
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membrane-associated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-a, DAP-1-b, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP, through the guanylate kinase domain. GKAP is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. GKAP is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  PSD95 binding protein 1; DAP 1 ALPHA; DAP 1; DAP 1 BETA; DAP-1; DAP-1-ALPHA; DAP-1-BETA; DAP1; Discs large Drosophila homolog associated protein 1; Discs large homolog associated protein 1; Disks large associated protein 1; Disks large associated protein 1, alpha isoform, included; Disks large associated protein 1, beta isoform, included; Disks large-associated protein 1; DLGAP 1; Dlgap1; DLGP1_HUMAN; GKAP; GKAP/SAPAP; GKPA/SAPAP; Guanylate kinase associated protein; Guanylate kinase-associated protein; hGKAP; KIAA4162; MGC88156; mKIAA4162; PSD 95/SAP90 binding protein 1; PSD-95/SAP90-binding protein 1; SAP90/PSD 95 associated protein 1; SAP90/PSD-95-associated protein 1; SAPAP 1; SAPAP1.
• Also known as
  SAPAP1/DLGAP1 Polyclonal Antibody
• Other name
  Anti-SAPAP1/DLGAP1 Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  SAPAP1/DLGAP1  
• Gene symbol
  DLGAP1, DLGAP1-AS4, DLGAP1-AS2, DLGAP1-AS5, DLGAP1-AS3, DLGAP1-AS1
• Short name
  Anti-SAPAP1/DLGAP1
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  SAPAP1/DLGAP1 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:2905
• Gene
  DLGAP1
• Long gene name
  DLG associated protein 1
• Synonyms gene name
  • discs, large (Drosophila) homolog-associated protein 1
  • discs large homolog associated protein 1
• Synonyms
  • GKAP
  • SAPAP1
  • DAP-1
• GenBank acession
  • AB000277
• Locus
  18p11.31
• Discovery year
  1999-02-23
• Entrez gene record
  9229
• Pubmed identfication
  • 9024696
  • 9286858
• VEGA ID
  OTTHUMG00000131537

Gene info

• Identity
  HGNC:44333
• Gene
  DLGAP1-AS4
• Long gene name
  DLGAP1 antisense RNA 4
• Synonyms gene name
  • DLGAP1 antisense RNA 4 (non-protein coding)
• GenBank acession
  • BI755422
  • CK005798
• Locus
  18p11.31
• Discovery year
  2012-08-13
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000178387

Gene info

• Identity
  HGNC:28146
• Gene
  DLGAP1-AS2
• Long gene name
  DLGAP1 antisense RNA 2
• Synonyms gene name
  • DLGAP1 antisense RNA 2 (non-protein coding)
• Synonyms
  • MGC11082
• GenBank acession
  • BC005130
• Locus
  18p11.31
• Discovery year
  2012-08-13
• Entrez gene record
  84777
• Pubmed identfication
  • 31899508
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000177864

Gene info

• Identity
  HGNC:27586
• Gene
  DLGAP1-AS5
• Long gene name
  DLGAP1 antisense RNA 5
• Synonyms gene name
  • DLGAP1 antisense RNA 5 (non-protein coding)
• Locus
  18p11.31
• Discovery year
  2012-08-13
• Entrez gene record
  284215
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000176106

Gene info

• Identity
  HGNC:27317
• Gene
  DLGAP1-AS3
• Long gene name
  DLGAP1 antisense RNA 3
• Synonyms gene name
  • DLGAP1 antisense RNA 3 (non-protein coding)
• Locus
  18p11.31
• Discovery year
  2012-08-13
• Entrez gene record
  201477
• Pubmed identfication
  • 12477932
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000178391

Gene info

• Identity
  HGNC:31676
• Gene
  DLGAP1-AS1
• Long gene name
  DLGAP1 antisense RNA 1
• Synonyms gene name
  • DLGAP1 antisense RNA 1 (non-protein coding)
• Synonyms
  • HsT914
  • FLJ35776
• Locus
  18p11.31
• Discovery year
  2012-08-13
• Entrez gene record
  649446
• Pubmed identfication
  • 31949128
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000177863

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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