Anti-PLC beta3 (Ser1105) (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-3341R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  PLC beta3 Ser1105
• Specificity
  This antibody reacts specifically with PLC beta3 (Ser1105)
• Modification
  Phosphorylation
• Modification site
  Ser1105
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic phosphopeptide derived from human PLC beta3 around the phosphorylation site of Ser1105
• Gene ID
  5331
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  Phospholipase C is a key enzyme in phosphatidylinositol (PIP2) metabolism and lipid signaling pathways. The Phospholipase C family consists of 13 isozymes split between six subfamilies. Phospholipase C beta is activated by G protein subunits.
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  Phospholipase C beta 3; Phospholipase C beta 3 phosphatidylinositol specic; PLC beta 3; PLCB3 antibody 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase beta 3; Phosphoinositide phospholipase C; PLCB3_HUMAN.
• Also known as
  PLC beta3 (Ser1105) Polyclonal Antibody
• Other name
  Anti-PLC beta3 (Ser1105) Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  PLC   beta3   Ser1105  
• Gene symbol
  PLCB1, PLCL1, PLCG1, PLCH2, PDIA3
• Short name
  Anti-PLC beta3 (Ser1105)
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  PLC beta3 (Ser1105) Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:15917
• Gene
  PLCB1
• Long gene name
  phospholipase C beta 1
• Synonyms gene name
  • phospholipase C, beta 1 (phosphoinositide-specific)
• Synonyms
  • KIAA0581
  • PLC-I
  • PLC154
• Synonyms name
  • phosphoinositide phospholipase C
• GenBank acession
  • AB011153
• Locus
  20p12.3
• Discovery year
  2001-06-21
• Entrez gene record
  23236
• Pubmed identfication
  • 10760467
  • 11118617
• Classification
  • Phospholipases
  • C2 domain containing phospholipases
• VEGA ID
  OTTHUMG00000031849

Gene info

• Identity
  HGNC:9063
• Gene
  PLCL1
• Long gene name
  phospholipase C like 1 (inactive)
• Synonyms gene
  • PLCE
• Synonyms gene name
  • phospholipase C, epsilon
  • phospholipase C-like 1
  • phospholipase C like 1
• Synonyms
  • PLC-L
  • PLCL
  • PRIP
  • PPP1R127
• Synonyms name
  • phospholipase C related, but catalytically inactive protein
  • protein phosphatase 1, regulatory subunit 127
• GenBank acession
  • D42108
• Locus
  2q33.1
• Discovery year
  1995-12-12
• Entrez gene record
  5334
• Pubmed identfication
  • 7633416
• RefSeq identity
  • NM_006226
• Classification
  • Protein phosphatase 1 regulatory subunits
  • C2 domain containing phospholipases
• VEGA ID
  OTTHUMG00000132750

Gene info

• Identity
  HGNC:9065
• Gene
  PLCG1
• Long gene name
  phospholipase C gamma 1
• Synonyms gene
  • PLC1
• Synonyms gene name
  • phospholipase C, gamma 1 (formerly subtype 148)
  • phospholipase C, gamma 1
• Synonyms
  • PLC148
  • PLC-II
  • PLCgamma1
  • NCKAP3
• GenBank acession
  • M34667
• Locus
  20q12
• Discovery year
  1989-05-31
• Entrez gene record
  5335
• Pubmed identfication
  • 2167438
  • 3254788
• RefSeq identity
  • NM_182811
• Classification
  • Pleckstrin homology domain containing
  • MicroRNA protein coding host genes
  • Phospholipases
  • SH2 domain containing
  • C2 domain containing phospholipases
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000033082

Gene info

• Identity
  HGNC:29037
• Gene
  PLCH2
• Long gene name
  phospholipase C eta 2
• Synonyms gene
  • PLCL4
• Synonyms gene name
  • phospholipase C-like 4
  • phospholipase C, eta 2
• Synonyms
  • KIAA0450
  • PLCeta2
  • RP3-395M20.1
  • PLC-eta2
• Synonyms name
  • 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2
• GenBank acession
  • AB007919
• Locus
  1p36.32
• Discovery year
  2004-07-28
• Entrez gene record
  9651
• Pubmed identfication
  • 15899900
• RefSeq identity
  • NM_014638
• Classification
  • EF-hand domain containing
  • Phospholipases
• VEGA ID
  OTTHUMG00000000719

Gene info

• Identity
  HGNC:4606
• Gene
  PDIA3
• Long gene name
  protein disulfide isomerase family A member 3
• Synonyms gene
  • GRP58
• Synonyms gene name
  • glucose regulated protein, 58kDa
  • protein disulfide isomerase-associated 3
  • protein disulfide isomerase family A, member 3
• Synonyms
  • P58
  • ERp61
  • ERp57
  • ERp60
  • GRP57
  • PI-PLC
  • HsT17083
• Locus
  15q15.3
• Discovery year
  1997-06-09
• Entrez gene record
  2923
• Pubmed identfication
  • 8974399
• RefSeq identity
  • NM_005313
• Classification
  • Protein disulfide isomerases
• VEGA ID
  OTTHUMG00000044444

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Product files

Similar products