Anti-IRAK1BP1 (Polyclonal), Biotin
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Catalog numberGENTObs-16694R-Biotin
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Price:
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withBiotin
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptideIRAK1BP1
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SpecificityThis antibody may exhibit a minor secondary cross-reactivity with SMPD5 due to a 63% contiguous sequence similarity over the immunogen range. IRAK1BP1 Biotin
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ModificationNo modification has been applied to this antibody
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Modification siteNone
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsCytoplasm, Nucleus
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Antigen SourceKLH conjugated synthetic peptide derived from human IRAK1BP1.
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Gene ID134728
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Swiss ProtQ5VVH5
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ApplicationsWB, IHC-P
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Applications with corresponding dilutionsWB(1:100-1000), IHC-P(1:100-500)
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Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationComponent of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity (By similarity).
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emissionN/A
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SynonymsAIP70; SIMPL; Interleukin-1 receptor-associated kinase 1-binding protein 1; IRAK1-binding protein 1; IRAK1BP1
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Also known asIRAK1BP1 Polyclonal Antibody Biotin
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Other nameAnti-IRAK1BP1 Polyclonal Biotin
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesBiotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
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ConjugationBiotinylated
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Gene target
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Gene symbolIRAK1BP1
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Short nameAnti-IRAK1BP1 Biotin
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TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeImmunoglobulin G (IgG)
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LabelBiotin
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Alternative nameIRAK1BP1 Polyclonal Antibody, Biotin Conjugated
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Alternative techniquepolyclonals, antibodies
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Alternative to gene targetinterleukin-1 receptor-associated kinase 1 binding protein 1, IRAK1BP1 and IDBG-93345 and ENSG00000146243 and 134728, protein binding, nuclei, Irak1bp1 and IDBG-188214 and ENSMUSG00000032251 and 65099, IRAK1BP1 and IDBG-630000 and ENSBTAG00000020825 and 782235
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 receptor associated kinase 1 binding protein 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-07-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data