Anti-HB-EGF (Polyclonal), ALEXA Fluor 594
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Catalog numberGENTObs-3576R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptideHB-EGF
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SpecificityThis antibody reacts specifically with HB-EGF
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ModificationNo modification has been applied to this antibody
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Modification siteNone
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsExtracellular
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Antigen SourceKLH conjugated synthetic peptide derived from human HB-EGF/DTSF
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Gene ID1839
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Swiss ProtQ99075
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ApplicationsIF(IHC-P)
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Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
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Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationGrowth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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SynonymsDTR; DTS; DTSF; HEGFL; Proheparin-binding EGF-like growth factor; HBEGF
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Also known asHB-EGF Polyclonal Antibody
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Other nameAnti-HB-EGF Polyclonal
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Gene target
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Gene symbolEGF, HMHB1, KRT84, HBEGF, KRT81, KRT85, KRT83, KRT82, PEG10
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Short nameAnti-HB-EGF
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TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameHB-EGF Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniquepolyclonals, antibodies
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Alternative to gene targetepidermal growth factor, HOMG4 and URG, EGF and IDBG-34100 and ENSG00000138798 and 1950, transmembrane receptor protein tyrosine kinase activator activity, Extracellular, Egf and IDBG-193432 and ENSMUSG00000028017 and 13645
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Gene info
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Identity
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Gene
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Long gene nameepidermal growth factor
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Synonyms gene name
- epidermal growth factor (beta-urogastrone)
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namehistocompatibility minor HB-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-07-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Minor histocompatibility antigens
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namekeratin 84
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Synonyms gene
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Synonyms gene name
- keratin, hair, basic, 4
- keratin 84, type II
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Keratins, type II
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameheparin binding EGF like growth factor
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Synonyms gene
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Synonyms gene name
- diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor)
- heparin-binding EGF-like growth factor
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namekeratin 81
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Synonyms gene
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Synonyms gene name
- keratin, hair, basic, 1
- keratin 81, type II
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Keratins, type II
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namekeratin 85
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Synonyms gene
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Synonyms gene name
- keratin, hair, basic, 5
- keratin 85, type II
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-21
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Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Keratins, type II
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VEGA ID
Gene info
-
Identity
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Gene
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Long gene namekeratin 83
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Synonyms gene
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Synonyms gene name
- keratin, hair, basic, 3
- keratin 83, type II
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Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1998-04-21
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Keratins, type II
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
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Long gene namekeratin 82
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Synonyms gene
-
Synonyms gene name
- keratin, hair, basic, 2
- keratin 82, type II
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Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1998-04-21
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Keratins, type II
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepaternally expressed 10
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-11-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Retrotransposon Gag like
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data