Anti-FOXG1/BF-1 (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-11557R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  FOXG1/BF-1
• Specificity
  This antibody reacts specifically with FOXG1/BF-1
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic peptide derived from human FOXG1
• Gene ID
  N/A
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  The winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1), also known as foxg1, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (1–4). WH proteins are a family of putative transcriptional regulators with diverse roles in development, and are characterized by a highly conserved DNA binding structure, the WH domain (1,5,6). BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, such as the cerebral cortex and basal ganglia (1). The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (1,7). BF-1 is expressed by E8.5 in telencephalic progenitors (1). It may also regulate the response of cerebral cortical progenitors to environmental cues (1).
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  BF 1; BF 2; BF-1; BF-2; BF1; BF2 ; Brain factor 1; Brain factor 2; FHKL; FKH2; FKHL1; FKHL2; FKHL2; FKHL3; FKHL4; Forkhead box G1A; Forkhead box G1B; Forkhead box protein G1; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead drosophila homolog like 2; Forkhead like 1; Forkhead like 2; FOXG1_HUMAN.
• Also known as
  FOXG1/BF-1 Polyclonal Antibody
• Other name
  Anti-FOXG1/BF-1 Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  FOXG1/BF-1  
• Gene symbol
  FOXG1-AS1, CFB, PRDM1, HIVEP1, FOXG1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1
• Short name
  Anti-FOXG1/BF-1
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  FOXG1/BF-1 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:50663
• Gene
  FOXG1-AS1
• Long gene name
  FOXG1 antisense RNA 1
• Synonyms gene name
  • FOXG1 antisense RNA 1 (head to head)
• Synonyms
  • FOXG1-AS
• GenBank acession
  • DA239559
• Locus
  14q12
• Discovery year
  2014-06-04
• Entrez gene record
  103695363
• Pubmed identfication
  • 24007600
• RefSeq identity
  • NR_125758
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000170343

Gene info

• Identity
  HGNC:1037
• Gene
  CFB
• Long gene name
  complement factor B
• Synonyms gene
  • BFD
  • BF
• Synonyms gene name
  • B-factor, properdin
• Synonyms
  • H2-Bf
• GenBank acession
  • L15702
• Locus
  6p21.33
• Discovery year
  1986-01-01
• Entrez gene record
  629
• RefSeq identity
  • NM_001710
• Classification
  • Complement system activation components
  • Sushi domain containing
• VEGA ID
  OTTHUMG00000031198
• Locus Specific Databases
  • LRG_136

Gene info

• Identity
  HGNC:9346
• Gene
  PRDM1
• Long gene name
  PR/SET domain 1
• Synonyms gene
  • BLIMP1
• Synonyms gene name
  • PR domain containing 1, with ZNF domain
  • PR domain 1
• Synonyms
  • PRDI-BF1
• Locus
  6q21
• Discovery year
  1994-09-14
• Entrez gene record
  639
• Pubmed identfication
  • 1851123
• Classification
  • Zinc fingers C2H2-type
  • PR/SET domain family
• VEGA ID
  OTTHUMG00000015299

Gene info

• Identity
  HGNC:4920
• Gene
  HIVEP1
• Long gene name
  HIVEP zinc finger 1
• Synonyms gene
  • ZNF40
• Synonyms gene name
  • human immunodeficiency virus type I enhancer-binding protein 1
  • zinc finger protein 40
  • human immunodeficiency virus type I enhancer binding protein 1
• Synonyms
  • CIRIP
  • MBP-1
  • CRYBP1
  • PRDII-BF1
  • ZAS1
  • Schnurri-1
  • ZNF40A
• GenBank acession
  • J05011
• Locus
  6p24.1
• Discovery year
  1990-10-04
• Entrez gene record
  3096
• Pubmed identfication
  • 2108316
  • 2037300
  • 2504707
• RefSeq identity
  • NM_002114
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000014265

Gene info

• Identity
  HGNC:3811
• Gene
  FOXG1
• Long gene name
  forkhead box G1
• Synonyms gene
  • FKHL2
  • FOXG1B
  • FKHL4
  • FKH2
  • FKHL1
  • FOXG1C
  • FKHL3
  • FOXG1A
• Synonyms gene name
  • forkhead box G1B
  • forkhead box G1C
  • forkhead box G1A
• Synonyms
  • HFK2
  • QIN
  • BF1
  • HFK1
  • HFK3
  • HBF-3
• Synonyms name
  • brain factor 1
• Locus
  14q12
• Discovery year
  1994-12-07
• Entrez gene record
  2290
• Pubmed identfication
  • 7959731
  • 17260156
• Classification
  • Forkhead boxes
• VEGA ID
  OTTHUMG00000140187

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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