Anti-ARPC2/p34-ARC (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-12527R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  ARPC2/p34-ARC
• Specificity
  This antibody reacts specifically with ARPC2/p34-ARC
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  Cytoplasm
• Antigen Source
  KLH conjugated synthetic peptide derived from human ARPC2/p34-ARC
• Gene ID
  10109
• Swiss Prot
  O15144
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  ARC34; PRO2446; p34-Arc; PNAS-139; Actin-related protein 2/3 complex subunit 2; Arp2/3 complex 34 kDa subunit; ARPC2
• Also known as
  ARPC2/p34-ARC Polyclonal Antibody
• Other name
  Anti-ARPC2/p34-ARC Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  ARPC2/p34-ARC  
• Gene symbol
  ARPC2, ARPC1B, ARC, ARPC3, ARPC4, NOL3, ARPC5
• Short name
  Anti-ARPC2/p34-ARC
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  ARPC2/p34-ARC Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  activity-regulated cytoskeleton-associated protein, Arg3.1, ARC and IDBG-37634 and ENSG00000198576 and 23237, protein binding, Cell surfaces, Arc and IDBG-149967 and ENSMUSG00000022602 and 11838, ARC and IDBG-648018 and ENSBTAG00000021639 and 519403

Gene info

• Identity
  HGNC:705
• Gene
  ARPC2
• Long gene name
  actin related protein 2/3 complex subunit 2
• Synonyms gene name
  • actin related protein 2/3 complex, subunit 2 (34 kD)
  • actin related protein 2/3 complex subunit 2, 34kDa
• Synonyms
  • p34-Arc
  • ARC34
• GenBank acession
  • AF006085
• Locus
  2q35
• Discovery year
  1999-08-06
• Entrez gene record
  10109
• Pubmed identfication
  • 9359840
  • 9230079
• RefSeq identity
  • NM_005731
• Classification
  • Actin related protein 2/3 complex subunits
• VEGA ID
  OTTHUMG00000133618

Gene info

• Identity
  HGNC:704
• Gene
  ARPC1B
• Long gene name
  actin related protein 2/3 complex subunit 1B
• Synonyms gene name
  • actin related protein 2/3 complex, subunit 1B (41 kD)
  • actin related protein 2/3 complex subunit 1B, 41kDa
• Synonyms
  • ARC41
  • p40-ARC
  • p41-ARC
• Synonyms name
  • ARP2/3 protein complex subunit p41
  • actin related protein 2/3 complex, subunit 1A (41 kD)
• GenBank acession
  • AF006084
• Locus
  7q22.1
• Discovery year
  1999-08-06
• Entrez gene record
  10095
• Pubmed identfication
  • 9230079
  • 9359840
• RefSeq identity
  • NM_005720
• Classification
  • WD repeat domain containing
  • Actin related protein 2/3 complex subunits
• VEGA ID
  OTTHUMG00000154552
• Locus Specific Databases
  • LRG_1188

Gene info

• Identity
  HGNC:648
• Gene
  ARC
• Long gene name
  activity regulated cytoskeleton associated protein
• Synonyms
  • KIAA0278
  • Arg3.1
• GenBank acession
  • AF193421
• Locus
  8q24.3
• Discovery year
  2000-05-23
• Entrez gene record
  23237
• Pubmed identfication
  • 10970730
  • 17466953
• Classification
  • Gag like LTR retrotransposon derived genes
• VEGA ID
  OTTHUMG00000134310

Gene info

• Identity
  HGNC:706
• Gene
  ARPC3
• Long gene name
  actin related protein 2/3 complex subunit 3
• Synonyms gene name
  • actin related protein 2/3 complex, subunit 3 (21 kD)
  • actin related protein 2/3 complex subunit 3, 21kDa
• Synonyms
  • p21-Arc
  • ARC21
• GenBank acession
  • AF006086
• Locus
  12q24.11
• Discovery year
  1999-08-06
• Entrez gene record
  10094
• Pubmed identfication
  • 9230079
  • 9359840
• Classification
  • Actin related protein 2/3 complex subunits
• VEGA ID
  OTTHUMG00000134333

Gene info

• Identity
  HGNC:707
• Gene
  ARPC4
• Long gene name
  actin related protein 2/3 complex subunit 4
• Synonyms gene name
  • actin related protein 2/3 complex, subunit 4 (20 kD)
  • actin related protein 2/3 complex subunit 4, 20kDa
• Synonyms
  • p20-Arc
  • ARC20
• Synonyms name
  • Arp2/3 protein complex subunit p20
  • actin related protein 2/3 complex, subunit 4 (20 kD)
• GenBank acession
  • AF019888
• Locus
  3p25.3
• Discovery year
  1999-08-06
• Entrez gene record
  10093
• Pubmed identfication
  • 9230079
  • 9359840
• RefSeq identity
  • NM_001024959
• Classification
  • Actin related protein 2/3 complex subunits
• VEGA ID
  OTTHUMG00000133768

Gene info

• Identity
  HGNC:7869
• Gene
  NOL3
• Long gene name
  nucleolar protein 3
• Synonyms gene name
  • nucleolar protein 3 (apoptosis repressor with CARD domain)
• Synonyms
  • ARC
  • NOP30
  • MYP
  • CARD2
• GenBank acession
  • AF043244
• Locus
  16q22.1
• Discovery year
  1999-01-13
• Entrez gene record
  8996
• Pubmed identfication
  • 9560245
• Classification
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000173316

Gene info

• Identity
  HGNC:708
• Gene
  ARPC5
• Long gene name
  actin related protein 2/3 complex subunit 5
• Synonyms gene name
  • actin related protein 2/3 complex, subunit 5 (16 kD)
  • actin related protein 2/3 complex subunit 5, 16kDa
• Synonyms
  • p16-Arc
  • ARC16
  • dJ127C7.3
• Synonyms name
  • Arp2/3 protein complex subunit p16
• GenBank acession
  • AF017807
• Locus
  1q25.3
• Discovery year
  1999-08-06
• Entrez gene record
  10092
• Pubmed identfication
  • 9359840
  • 9230079
• RefSeq identity
  • NM_005717
• Classification
  • Actin related protein 2/3 complex subunits
• VEGA ID
  OTTHUMG00000035326

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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