OVA Conjugated Transcription Termination Factor, RNA polymerase I (TTF1)
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Catalog number
RPU50061-1mg
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Price
Please ask
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Size
1mg
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Estimated Turnaround Time
6-11 business days
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Gene Name
NA
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Alternative Names
RNA polymerase I termination factor
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Source
Chemical synthesis
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Purity
> 90%
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Application
Immunogen; SDS-PAGE; WB
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Shipping Conditions
Ice packs
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Storage conditions
Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
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Shelf life
1 year
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Restriction
For research use only. Not for diagnostic procedures.
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Gene target
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Gene symbol
TTF1, NKX2-1
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Short name
OVA Conjugated Transcription Termination Factor, RNA polymerase I (TTF1)
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Technique
antibody Conjugates, RNAs are to store at -70 C
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Species
Homo sapiens (Human)
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Alternative name
OVA coupled Transcription Termination Factor, RNA polymerizing enzyme I (TTF1)
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Gene info
Gene info
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Identity
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Gene
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Long gene name
NK2 homeobox 1
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Synonyms gene
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Synonyms gene name
- benign chorea
- thyroid transcription factor 1
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Synonyms
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Locus
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Discovery year
1992-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NKL subclass homeoboxes and pseudogenes
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VEGA ID
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