OVA Conjugated Cholinergic Receptor, Muscarinic 3 (CHRM3)
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Catalog number
RPU50193-100ug
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Price
Please ask
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Size
100ug
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Estimated Turnaround Time
6-11 business days
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Gene Name
NA
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Alternative Names
CHR-M3; HM3; M-AChRM3; Muscarinic Acetylcholine Receptor M3; Cholinergic Receptor,Muscarinic 3
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Source
Chemical synthesis
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Purity
> 90%
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Application
Immunogen; SDS-PAGE; WB
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Shipping Conditions
Ice packs
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Storage conditions
Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
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Shelf life
1 year
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Restriction
For research use only. Not for diagnostic procedures.
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
CHRM3, CHRM3-AS2, CHRM3-AS1
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Short name
OVA Conjugated Cholinergic Receptor, Muscarinic 3 (CHRM3)
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Technique
antibody Conjugates
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Species
Homo sapiens (Human)
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Alternative name
OVA coupled Cholinergic Receptor, Muscarinic 3 (CHRM3)
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Gene info
Gene info
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Identity
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Gene
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Long gene name
CHRM3 antisense RNA 2
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Synonyms gene name
- CHRM3 antisense RNA 2 (non-protein coding)
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GenBank acession
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Locus
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Discovery year
2012-02-09
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Entrez gene record
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
CHRM3 antisense RNA 1
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Synonyms gene name
- CHRM3 antisense RNA 1 (non-protein coding)
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GenBank acession
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Locus
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Discovery year
2012-02-09
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Classification
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VEGA ID
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